Guidelines for the nomenclature of the human heat shock proteins

Harm H. Kampinga*, Jurre Hageman, Michel J. Vos, Hiroshi Kubota, Robert M. Tanguay, Elspeth A. Bruford, Michael E. Cheetham, B. Chen, Lawrence E. Hightower

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    The expanding number of members in the various human heat shock protein (HSP) families and the inconsistencies in their nomenclature have often led to confusion. Here, we propose new guidelines for the nomenclature of the human HSP families, HSPH (HSP110), HSPC (HSP90), HSPA (HSP70), DNAJ (HSP40), and HSPB (small HSP) as well as for the human chaperonin families HSPD/E (HSP60/HSP10) and CCT (TRiC). The nomenclature is based largely on the more consistent nomenclature assigned by the HUGO Gene Nomenclature Committee and used in the National Center of Biotechnology Information Entrez Gene database for the heat shock genes. In addition to this nomenclature, we provide a list of the human Entrez Gene IDs and the corresponding Entrez Gene IDs for the mouse orthologs.

    Original languageEnglish
    Pages (from-to)105-111
    Number of pages7
    JournalCell stress & chaperones
    Volume14
    Issue number1
    DOIs
    Publication statusPublished - Jan-2009

    Keywords

    • Nomenclature
    • Human heat shock proteins
    • HUMAN GENOME
    • HSP90 FAMILY
    • GENES
    • EVOLUTION
    • CLONING
    • HSP110

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