Hepatitis in a patient with SLE: Is it autoimmune hepatitis?

A. Kooy; L. J.M. De Heide; H. J.H. Engelkens; A. H. Mulder; M. Van Hagen; S. W. Schalm

doi:10.1016/0300-2977(95)00072-0

Hepatitis in a patient with SLE: Is it autoimmune hepatitis?

A. Kooy^*
, L. J.M. De Heide
, H. J.H. Engelkens
, A. H. Mulder
, M. Van Hagen
, S. W. Schalm

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

In a patient with systemic lupus erythematosus (SLE), we considered the diagnosis of autoimmune hepatitis (AIH) in view of raised serum aminotransferases, hypergammaglobulinaemia, antinuclear antibodies (titre 1:10240), seronegative of markers for viral hepatitis and absence of recent hepatotoxic drug usage. The diagnosis of AIH was supported by using the scoring system, recently developed by the International Autoimmune Hepatitis Group and the excellent response to treatment with prednisone. Liver histology, however, showed no characteristic features of AIH. The relevance of liver histology and scoring for AIH in SLE with hepatic involvement is discussed.

Original language	English
Pages (from-to)	128-132
Number of pages	5
Journal	Netherlands Journal of Medicine
Volume	48
Issue number	4
DOIs	https://doi.org/10.1016/0300-2977(95)00072-0
Publication status	Published - Apr-1996
Externally published	Yes

Keywords

autoimmune hepatitis, scoring system
hepatic involvement
liver biopsy
systemic lupus erythematosus

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Hepatitis in a patient with SLEFinal publisher's version, 452 KBLicence: Taverne

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title = "Hepatitis in a patient with SLE: Is it autoimmune hepatitis?",

abstract = "In a patient with systemic lupus erythematosus (SLE), we considered the diagnosis of autoimmune hepatitis (AIH) in view of raised serum aminotransferases, hypergammaglobulinaemia, antinuclear antibodies (titre 1:10240), seronegative of markers for viral hepatitis and absence of recent hepatotoxic drug usage. The diagnosis of AIH was supported by using the scoring system, recently developed by the International Autoimmune Hepatitis Group and the excellent response to treatment with prednisone. Liver histology, however, showed no characteristic features of AIH. The relevance of liver histology and scoring for AIH in SLE with hepatic involvement is discussed.",

keywords = "autoimmune hepatitis, scoring system, hepatic involvement, liver biopsy, systemic lupus erythematosus",

author = "A. Kooy and \{De Heide\}, \{L. J.M.\} and Engelkens, \{H. J.H.\} and Mulder, \{A. H.\} and \{Van Hagen\}, M. and Schalm, \{S. W.\}",

year = "1996",

month = apr,

doi = "10.1016/0300-2977(95)00072-0",

language = "English",

volume = "48",

pages = "128--132",

journal = "Netherlands Journal of Medicine",

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publisher = "van Zuiden Communications BV.",

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}

TY - JOUR

T1 - Hepatitis in a patient with SLE

T2 - Is it autoimmune hepatitis?

AU - Kooy, A.

AU - De Heide, L. J.M.

AU - Engelkens, H. J.H.

AU - Mulder, A. H.

AU - Van Hagen, M.

AU - Schalm, S. W.

PY - 1996/4

Y1 - 1996/4

N2 - In a patient with systemic lupus erythematosus (SLE), we considered the diagnosis of autoimmune hepatitis (AIH) in view of raised serum aminotransferases, hypergammaglobulinaemia, antinuclear antibodies (titre 1:10240), seronegative of markers for viral hepatitis and absence of recent hepatotoxic drug usage. The diagnosis of AIH was supported by using the scoring system, recently developed by the International Autoimmune Hepatitis Group and the excellent response to treatment with prednisone. Liver histology, however, showed no characteristic features of AIH. The relevance of liver histology and scoring for AIH in SLE with hepatic involvement is discussed.

AB - In a patient with systemic lupus erythematosus (SLE), we considered the diagnosis of autoimmune hepatitis (AIH) in view of raised serum aminotransferases, hypergammaglobulinaemia, antinuclear antibodies (titre 1:10240), seronegative of markers for viral hepatitis and absence of recent hepatotoxic drug usage. The diagnosis of AIH was supported by using the scoring system, recently developed by the International Autoimmune Hepatitis Group and the excellent response to treatment with prednisone. Liver histology, however, showed no characteristic features of AIH. The relevance of liver histology and scoring for AIH in SLE with hepatic involvement is discussed.

KW - autoimmune hepatitis, scoring system

KW - hepatic involvement

KW - liver biopsy

KW - systemic lupus erythematosus

UR - https://www.scopus.com/pages/publications/0029996818

U2 - 10.1016/0300-2977(95)00072-0

DO - 10.1016/0300-2977(95)00072-0

M3 - Article

C2 - 8999359

AN - SCOPUS:0029996818

SN - 0300-2977

VL - 48

SP - 128

EP - 132

JO - Netherlands Journal of Medicine

JF - Netherlands Journal of Medicine

IS - 4

ER -

Hepatitis in a patient with SLE: Is it autoimmune hepatitis?

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