Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding

C. H. C. M. Buys*, W. L. Gouw, J. A. M. Blenkers, C. H. van Dalen

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    Distamycin A/DAPI staining and sequential C-banding of human lymphocyte chromosomes reveals the regular occurrence of differentially staining subfractions of chromosome 9 constitutive heterochromatin. These subfractions are regionally organized as two subsegments: a distal one, which fluoresces brightly with DAPI after preincubation with distamycin A and a proximal one, which stains intensely with Giemsa after sequential C-banding. Observations are presented that indicate an occasionally independent genetic behavior of these heterochromatin subfractions.
    Original languageEnglish
    Pages (from-to)28-30
    Number of pages3
    JournalHUMAN GENETICS
    Volume57
    Issue number1
    DOIs
    Publication statusPublished - 1981

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