Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding

C. H. C. M. Buys; W. L. Gouw; J. A. M. Blenkers; C. H. van Dalen

doi:10.1007/BF00271162

Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding

C. H. C. M. Buys^*, W. L. Gouw, J. A. M. Blenkers, C. H. van Dalen

^*Corresponding author for this work

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Abstract

Distamycin A/DAPI staining and sequential C-banding of human lymphocyte chromosomes reveals the regular occurrence of differentially staining subfractions of chromosome 9 constitutive heterochromatin. These subfractions are regionally organized as two subsegments: a distal one, which fluoresces brightly with DAPI after preincubation with distamycin A and a proximal one, which stains intensely with Giemsa after sequential C-banding. Observations are presented that indicate an occasionally independent genetic behavior of these heterochromatin subfractions.

Original language	English
Pages (from-to)	28-30
Number of pages	3
Journal	HUMAN GENETICS
Volume	57
Issue number	1
DOIs	https://doi.org/10.1007/BF00271162
Publication status	Published - 1981

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Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding
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title = "Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding",

abstract = "Distamycin A/DAPI staining and sequential C-banding of human lymphocyte chromosomes reveals the regular occurrence of differentially staining subfractions of chromosome 9 constitutive heterochromatin. These subfractions are regionally organized as two subsegments: a distal one, which fluoresces brightly with DAPI after preincubation with distamycin A and a proximal one, which stains intensely with Giemsa after sequential C-banding. Observations are presented that indicate an occasionally independent genetic behavior of these heterochromatin subfractions.",

author = "Buys, {C. H. C. M.} and Gouw, {W. L.} and Blenkers, {J. A. M.} and {van Dalen}, {C. H.}",

year = "1981",

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volume = "57",

pages = "28--30",

journal = "HUMAN GENETICS",

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T1 - Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding

AU - Buys, C. H. C. M.

AU - Gouw, W. L.

AU - Blenkers, J. A. M.

AU - van Dalen, C. H.

PY - 1981

Y1 - 1981

N2 - Distamycin A/DAPI staining and sequential C-banding of human lymphocyte chromosomes reveals the regular occurrence of differentially staining subfractions of chromosome 9 constitutive heterochromatin. These subfractions are regionally organized as two subsegments: a distal one, which fluoresces brightly with DAPI after preincubation with distamycin A and a proximal one, which stains intensely with Giemsa after sequential C-banding. Observations are presented that indicate an occasionally independent genetic behavior of these heterochromatin subfractions.

AB - Distamycin A/DAPI staining and sequential C-banding of human lymphocyte chromosomes reveals the regular occurrence of differentially staining subfractions of chromosome 9 constitutive heterochromatin. These subfractions are regionally organized as two subsegments: a distal one, which fluoresces brightly with DAPI after preincubation with distamycin A and a proximal one, which stains intensely with Giemsa after sequential C-banding. Observations are presented that indicate an occasionally independent genetic behavior of these heterochromatin subfractions.

U2 - 10.1007/BF00271162

DO - 10.1007/BF00271162

M3 - Article

SN - 0340-6717

VL - 57

SP - 28

EP - 30

JO - HUMAN GENETICS

JF - HUMAN GENETICS

IS - 1

ER -

Heterogeneity of human chromosome 9 constitutive heterochromatin as revealed by sequential distamycin A/DAPI staining and C-banding

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