High-pitch versus sequential mode for coronary calcium in individuals with a high heart rate: Potential for dose reduction

Marleen Vonder, Rozemarijn Vliegenthart, Merel A Kaatee, Carlijn M van der Aalst, Peter M A van Ooijen, Geertruida H de Bock, Jan Willem Gratama, Dirkjan Kuijpers, Harry J de Koning, Matthijs Oudkerk*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Abstract

Background: To determine the impact of high-pitch spiral acquisition on radiation dose and cardiovascular disease (CVD) risk stratification by coronary artery calcium (CAC) assessment with computed tomography in individuals with a high heart rate.

Methods: Of the ROBINSCA trial, 1990 participants with regular rhythm and heart rates > 65 beats per minute (bpm) were included. As reference, 390 participants with regular heart rates

Results: A similar percentage of participants with low heart rates and high heart rates had a positive CAC score in data sets acquired in high-pitch spiral (low heart rate: 57.7%, high heart rate: 55.8%) and sequential mode (58.0%, 54.7%, p = n.s.). The median absolute difference in Agatston scores between acquisition modes was 14.2% and 9.2%, for the high and low heart rate groups, respectively. Excellent agreement for risk categorization between the two data acquisition modes was found for the high (kappa = 0.927) and low (kappa = 0.946) heart rate groups. Radiation dose was 48% lower for high-pitch spiral versus sequential acquisitions.

Conclusion: Radiation dose for the quantification of coronary calcium can be reduced by 48% when using the high-pitch spiral acquisition mode compared to the sequential mode in participants with a regular high heart rate. CVD risk stratification agreement between the two modes of data acquisition is excellent.

Original languageEnglish
Pages (from-to)298-304
Number of pages7
JournalJournal of Cardiovascular Computed Tomography
Volume12
Issue number4
Early online date1-Mar-2018
DOIs
Publication statusPublished - 2018

Keywords

  • Coronary vessels
  • Heart rate
  • Cardiovascular diseases
  • Tomography
  • X-ray computed
  • ARTERY CALCIUM
  • COMPUTED-TOMOGRAPHY
  • ITERATIVE RECONSTRUCTION
  • INTERSCAN VARIABILITY
  • CT
  • REPRODUCIBILITY
  • QUANTIFICATION
  • CALCIFICATION
  • GUIDELINES
  • PHANTOM

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