Background: To determine the impact of high-pitch spiral acquisition on radiation dose and cardiovascular disease (CVD) risk stratification by coronary artery calcium (CAC) assessment with computed tomography in individuals with a high heart rate.
Methods: Of the ROBINSCA trial, 1990 participants with regular rhythm and heart rates > 65 beats per minute (bpm) were included. As reference, 390 participants with regular heart rates
Results: A similar percentage of participants with low heart rates and high heart rates had a positive CAC score in data sets acquired in high-pitch spiral (low heart rate: 57.7%, high heart rate: 55.8%) and sequential mode (58.0%, 54.7%, p = n.s.). The median absolute difference in Agatston scores between acquisition modes was 14.2% and 9.2%, for the high and low heart rate groups, respectively. Excellent agreement for risk categorization between the two data acquisition modes was found for the high (kappa = 0.927) and low (kappa = 0.946) heart rate groups. Radiation dose was 48% lower for high-pitch spiral versus sequential acquisitions.
Conclusion: Radiation dose for the quantification of coronary calcium can be reduced by 48% when using the high-pitch spiral acquisition mode compared to the sequential mode in participants with a regular high heart rate. CVD risk stratification agreement between the two modes of data acquisition is excellent.
- Coronary vessels
- Heart rate
- Cardiovascular diseases
- X-ray computed
- ARTERY CALCIUM
- ITERATIVE RECONSTRUCTION
- INTERSCAN VARIABILITY