High protein S activity due to C4b-binding protein deficiency in a 34-year-old Surinamese female with ischemic retinopathy

Rene Mulder*, Jeroen K. de Vries, Rogier P. H. M. Muskens, Andre B. Mulder, Michael V. Lukens

*Corresponding author for this work

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    Abstract

    Key Clinical Message

    In this study, we present the first case of a 34-year-old Surinamese female with ischemic retinopathy and increased free protein S due to C4BP deficiency. Possibly, the low PS/C4BP complex level has increased the risk of arterial thrombosis in our patient.

    Original languageEnglish
    Pages (from-to)935-938
    Number of pages4
    JournalClinical case reports
    Volume6
    Issue number5
    DOIs
    Publication statusPublished - May-2018

    Keywords

    • C4BP
    • C4BPA
    • free protein S
    • p.I300T
    • p.R240H
    • retinopathy
    • BETA-CHAIN
    • INHIBITION
    • BINDING
    • PATHWAY
    • COMPLEX
    • PLASMA

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