Higher patient perceived side effects related to higher daily doses of inhaled corticosteroids in the community: A cross-sectional analysis

Juliet M. Foster*, Lorna Aucott, Rik H. W. van der Werf, Mariken J. van der Meijden, Gysbert Schraa, Dirkje S. Postma, Thys van der Molen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

Abstract

The range and extent of inhaled corticosteroid (ICS) side effects experienced by patients in the general community are likely to be underestimated. Aims: To identify the side effects of ICS perceived by patients in the community and, through the use of a self-report questionnaire, measure their intensity, prevalence and relationship with daily medication dose. Methods: Focus groups and in-depth interviews were conducted to identify side effects that patients associated with their use of ICS. In an international multicentre cross-sectional survey, 395 inhaler users from community pharmacy (mean age 50, 53% female), divided into 4 daily dosage groups (beta(2)-agonist without ICS n = 66, beclometasone dipropionate (BDP) equivalent ICS low dose 800 mu g, n = 69) reported how much they were affected by these side effects on a 7-point Likert scale.

Original languageEnglish
Pages (from-to)1318-1336
Number of pages19
JournalRespiratory Medicine
Volume100
Issue number8
DOIs
Publication statusPublished - Aug-2006

Keywords

  • adverse effects
  • glucocorticoids
  • administration
  • inhalation
  • administration and dosage
  • ADVERSE DRUG-REACTIONS
  • ASTHMATIC-PATIENTS
  • RISK
  • AEROSOL
  • COUGH

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