Higher patient perceived side effects related to higher daily doses of inhaled corticosteroids in the community: A cross-sectional analysis

Juliet M. Foster; Lorna Aucott; Rik H. W. van der Werf; Mariken J. van der Meijden; Gysbert Schraa; Dirkje S. Postma; Thys van der Molen

doi:10.1016/j.rmed.2005.11.029

Higher patient perceived side effects related to higher daily doses of inhaled corticosteroids in the community: A cross-sectional analysis

Juliet M. Foster^*, Lorna Aucott, Rik H. W. van der Werf, Mariken J. van der Meijden, Gysbert Schraa, Dirkje S. Postma, Thys van der Molen

^*Corresponding author for this work

Groningen Research Institute for Asthma and COPD (GRIAC)

Research output: Contribution to journal › Article › Academic › peer-review

34 Citations (Scopus)

Abstract

The range and extent of inhaled corticosteroid (ICS) side effects experienced by patients in the general community are likely to be underestimated. Aims: To identify the side effects of ICS perceived by patients in the community and, through the use of a self-report questionnaire, measure their intensity, prevalence and relationship with daily medication dose. Methods: Focus groups and in-depth interviews were conducted to identify side effects that patients associated with their use of ICS. In an international multicentre cross-sectional survey, 395 inhaler users from community pharmacy (mean age 50, 53% female), divided into 4 daily dosage groups (beta(2)-agonist without ICS n = 66, beclometasone dipropionate (BDP) equivalent ICS low dose 800 mu g, n = 69) reported how much they were affected by these side effects on a 7-point Likert scale.

Original language	English
Pages (from-to)	1318-1336
Number of pages	19
Journal	Respiratory Medicine
Volume	100
Issue number	8
DOIs	https://doi.org/10.1016/j.rmed.2005.11.029
Publication status	Published - Aug-2006

Keywords

adverse effects
glucocorticoids
administration
inhalation
administration and dosage
ADVERSE DRUG-REACTIONS
ASTHMATIC-PATIENTS
RISK
AEROSOL
COUGH

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@article{c4dc1a53969e4696827c785792847f62,

title = "Higher patient perceived side effects related to higher daily doses of inhaled corticosteroids in the community: A cross-sectional analysis",

abstract = "The range and extent of inhaled corticosteroid (ICS) side effects experienced by patients in the general community are likely to be underestimated. Aims: To identify the side effects of ICS perceived by patients in the community and, through the use of a self-report questionnaire, measure their intensity, prevalence and relationship with daily medication dose. Methods: Focus groups and in-depth interviews were conducted to identify side effects that patients associated with their use of ICS. In an international multicentre cross-sectional survey, 395 inhaler users from community pharmacy (mean age 50, 53% female), divided into 4 daily dosage groups (beta(2)-agonist without ICS n = 66, beclometasone dipropionate (BDP) equivalent ICS low dose 800 mu g, n = 69) reported how much they were affected by these side effects on a 7-point Likert scale.",

keywords = "adverse effects, glucocorticoids, administration, inhalation, administration and dosage, ADVERSE DRUG-REACTIONS, ASTHMATIC-PATIENTS, RISK, AEROSOL, COUGH",

author = "Foster, {Juliet M.} and Lorna Aucott and {van der Werf}, {Rik H. W.} and {van der Meijden}, {Mariken J.} and Gysbert Schraa and Postma, {Dirkje S.} and {van der Molen}, Thys",

year = "2006",

month = aug,

doi = "10.1016/j.rmed.2005.11.029",

language = "English",

volume = "100",

pages = "1318--1336",

journal = "Respiratory Medicine",

issn = "0954-6111",

publisher = "W B SAUNDERS CO LTD",

number = "8",

}

TY - JOUR

T1 - Higher patient perceived side effects related to higher daily doses of inhaled corticosteroids in the community

T2 - A cross-sectional analysis

AU - Foster, Juliet M.

AU - Aucott, Lorna

AU - van der Werf, Rik H. W.

AU - van der Meijden, Mariken J.

AU - Schraa, Gysbert

AU - Postma, Dirkje S.

AU - van der Molen, Thys

PY - 2006/8

Y1 - 2006/8

N2 - The range and extent of inhaled corticosteroid (ICS) side effects experienced by patients in the general community are likely to be underestimated. Aims: To identify the side effects of ICS perceived by patients in the community and, through the use of a self-report questionnaire, measure their intensity, prevalence and relationship with daily medication dose. Methods: Focus groups and in-depth interviews were conducted to identify side effects that patients associated with their use of ICS. In an international multicentre cross-sectional survey, 395 inhaler users from community pharmacy (mean age 50, 53% female), divided into 4 daily dosage groups (beta(2)-agonist without ICS n = 66, beclometasone dipropionate (BDP) equivalent ICS low dose 800 mu g, n = 69) reported how much they were affected by these side effects on a 7-point Likert scale.

AB - The range and extent of inhaled corticosteroid (ICS) side effects experienced by patients in the general community are likely to be underestimated. Aims: To identify the side effects of ICS perceived by patients in the community and, through the use of a self-report questionnaire, measure their intensity, prevalence and relationship with daily medication dose. Methods: Focus groups and in-depth interviews were conducted to identify side effects that patients associated with their use of ICS. In an international multicentre cross-sectional survey, 395 inhaler users from community pharmacy (mean age 50, 53% female), divided into 4 daily dosage groups (beta(2)-agonist without ICS n = 66, beclometasone dipropionate (BDP) equivalent ICS low dose 800 mu g, n = 69) reported how much they were affected by these side effects on a 7-point Likert scale.

KW - adverse effects

KW - glucocorticoids

KW - administration

KW - inhalation

KW - administration and dosage

KW - ADVERSE DRUG-REACTIONS

KW - ASTHMATIC-PATIENTS

KW - RISK

KW - AEROSOL

KW - COUGH

U2 - 10.1016/j.rmed.2005.11.029

DO - 10.1016/j.rmed.2005.11.029

M3 - Article

SN - 0954-6111

VL - 100

SP - 1318

EP - 1336

JO - Respiratory Medicine

JF - Respiratory Medicine

IS - 8

ER -