Highly efficient ytterbium triflate catalyzed Michael additions of alpha-nitroesters in water

E Keller, B.L. Feringa

Research output: Contribution to journalArticleAcademicpeer-review

58 Citations (Scopus)
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Abstract

Michael additions of alpha-nitroesters with enones and alpha,beta-unsaturated aldehydes result in quantitative conversions to the corresponding 1,4-adducts by performing the reactions in water in the presence of ytterbium triflate as water-tolerant Lewis acid.

Original languageEnglish
Pages (from-to)842-&
Number of pages4
JournalSynlett
Volume1997
Issue number7
DOIs
Publication statusPublished - Jul-1997

Keywords

  • ytterbium triflate
  • Michael addition
  • alpha-nitroesters
  • water
  • ENANTIOSELECTIVE CONJUGATE ADDITION
  • CARBON BOND FORMATION
  • ORGANIC-SYNTHESIS
  • AQUEOUS-MEDIA
  • COMPLEXES

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