Histologic evaluation of the effect of formocresol and glutaraldehyde on the periapical tissues after endodontic treatment

J. C. Wemes*, H. W. B. Jansen, D. Purdell-Lewis, G. Boering

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    22 Citations (Scopus)


    The root canals of twelve pairs of human incisors without hard tissue or periodontal disease were treated with either formocresol or glutaraldehyde. The periapical reactions were compared histologically after periods varying between 6 and 8 weeks. A formocresol dressing always resulted in irritation of the periapical tissues, whereas little or no irritation was found after treatment with glutaraldehyde. It can be concluded that, after a vital pulpectomy, treatment of root canals with glutaraldehyde is faster than, as efficient as, and less irritating than treatment with formocresol.
    Original languageEnglish
    Pages (from-to)329-332
    Number of pages4
    JournalOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics
    Issue number3
    Publication statusPublished - 1982

    Cite this