Homeopathic Ligand-Free Palladium as a Catalyst in the Heck Reaction. A Comparison with a Palladacycle

André H.M. de Vries; Jan M.C.A. Mulders; John H.M. Mommers; Huub J.W. Henderickx; Johannes G. de Vries

Homeopathic Ligand-Free Palladium as a Catalyst in the Heck Reaction. A Comparison with a Palladacycle

André H.M. de Vries, Jan M.C.A. Mulders, John H.M. Mommers, Huub J.W. Henderickx, Johannes G. de Vries

Stratingh Institute for Chemistry

Research output: Contribution to journal › Article › Academic

571 Citations (Scopus)

789 Downloads (Pure)

Abstract

Ligand-free Pd(OAc)2 can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %. At higher concentrations palladium black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free palladium in Heck reactions of aryl bromides.

Original language	English
Number of pages	4
Journal	ChemInform
Volume	34
Issue number	51
Publication status	Published - 2003

Access to Document

2003OrgLettdeVriesAHMSupp.pdfFinal publisher's version, 124 KB
2003OrgLettdeVriesAHM.pdfFinal publisher's version, 73.3 KB

Handle.net

Persistent link

Cite this

@article{6c7078f0a6bd434c8fdac45fea9128fa,

title = "Homeopathic Ligand-Free Palladium as a Catalyst in the Heck Reaction. A Comparison with a Palladacycle",

abstract = "Ligand-free Pd(OAc)2 can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %. At higher concentrations palladium black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free palladium in Heck reactions of aryl bromides.",

author = "Vries, {Andr{\'e} H.M. de} and Mulders, {Jan M.C.A.} and Mommers, {John H.M.} and Henderickx, {Huub J.W.} and Vries, {Johannes G. de}",

note = "Relation: http://www.rug.nl/scheikunde/ date_submitted:2006 Rights: University of Groningen. Stratingh Institute",

year = "2003",

language = "English",

volume = "34",

journal = "ChemInform",

number = "51",

}

TY - JOUR

T1 - Homeopathic Ligand-Free Palladium as a Catalyst in the Heck Reaction. A Comparison with a Palladacycle

AU - Vries, André H.M. de

AU - Mulders, Jan M.C.A.

AU - Mommers, John H.M.

AU - Henderickx, Huub J.W.

AU - Vries, Johannes G. de

N1 - Relation: http://www.rug.nl/scheikunde/ date_submitted:2006 Rights: University of Groningen. Stratingh Institute

PY - 2003

Y1 - 2003

N2 - Ligand-free Pd(OAc)2 can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %. At higher concentrations palladium black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free palladium in Heck reactions of aryl bromides.

AB - Ligand-free Pd(OAc)2 can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %. At higher concentrations palladium black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free palladium in Heck reactions of aryl bromides.

M3 - Article

VL - 34

JO - ChemInform

JF - ChemInform

IS - 51

ER -