Homeopathic Ligand-Free Palladium as a Catalyst in the Heck Reaction. A Comparison with a Palladacycle

André H.M. de Vries, Jan M.C.A. Mulders, John H.M. Mommers, Huub J.W. Henderickx, Johannes G. de Vries

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Ligand-free Pd(OAc)2 can be used as a catalyst in the Heck reaction of aryl bromides as long as the amount of catalyst is kept between 0.01 and 0.1 mol %. At higher concentrations palladium black forms and the reaction stops. The actual catalyst is monomeric. Palladacycles merely serve as a source of ligand-free palladium in Heck reactions of aryl bromides.
Original languageEnglish
Number of pages4
Issue number51
Publication statusPublished - 2003

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