Hoofdpijn door geneesmiddelen: Aan de top van de meest gemelde bijwerkingen

Translated title of the contribution: At the top of the most reported adverse reactions. Drug-induced headache

M.C.H. De Groot, L.J. Stoker, E.P. Van Puijenbroek

    Research output: Contribution to journalArticleAcademicpeer-review

    1 Citation (Scopus)


    The Netherlands Pharmacovigilance Centre Lareb evaluates the reports as generated by the spontaneous adverse event reporting system in the Netherlands. This article describes the association between the adverse drug reactions (ADRs), headache and migraine and reported suspected drugs. In a case/non-case design, reporting odds ratios were calculated in order to analyse this association. Additionally the results of this analysis were compared with data from literature. Taken together, the ADRs headache and migraine are the second most reported ADR. The results of the analysis of the association between drugs and both ADRs in the Lareb data set are generally in accordance with literature data. Especially drugs causing vasodilative effects have often been associated with headache or migraine.
    Translated title of the contributionAt the top of the most reported adverse reactions. Drug-induced headache
    Original languageDutch
    Pages (from-to)1424-1428
    Number of pages5
    JournalPharmaceutisch Weekblad
    Issue number40
    Publication statusPublished - 4-Oct-2002


    • alfuzosin
    • aminoquinoline derivative
    • antinociceptive agent
    • beta adrenergic receptor blocking agent
    • calcium antagonist
    • carbasalate calcium
    • cholinergic receptor blocking agent
    • cisapride
    • cotrimoxazole
    • dihydropyridine derivative
    • dipyridamole
    • estrane derivative
    • felodipine
    • indometacin
    • ipratropium bromide
    • mebeverine
    • mefloquine
    • mesalazine
    • minocycline
    • nitrate
    • nitrofuran derivative
    • salazosulfapyridine
    • salmeterol
    • serotonin 1 antagonist
    • serotonin 2 antagonist
    • terfenadine
    • theophylline
    • tibolone
    • unindexed drug
    • verapamil
    • article
    • drug induced disease
    • drug surveillance program
    • headache
    • human
    • migraine
    • Netherlands
    • vasodilatation

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