Hypertension en orthostatic hypotension during use of monoamine oxidase (MAO) inhibitors

W T Zandee, J Alsma, T K Birkenhäger, A H VAN den Meiracker, M van Hoek, J Versmissen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademic

1 Citation (Scopus)


Monoamine oxidase (mao) inhibitors are antidepressants with potentially severe side-effects. For this reason, the registration of this drug was suspended for some time when safer alternatives became available. However, mao inhibitors can be very effective in cases where depression has proved to be treatment resistant. Consequently, last year tranylcypromine was re-registered for use in the Netherlands. Since mao inhibitors have been used only sporadically in the Netherlands over the last few years, health professionals have only limited knowledge about the side-effects. On the basis of a recent case, we discuss the two most important side-effects of using mao inhibitors, namely hypertension and orthostatic hypotension. We discuss the possible causes and suggest ways on which these two side-effects can be prevented, or treated, should they arise.

Translated title of the contributionHypertension en orthostatic hypotension during use of monoamine oxidase (MAO) inhibitors
Original languageDutch
Pages (from-to)366-371
Number of pages6
JournalTijdschrift voor Psychiatrie
Issue number6
Publication statusPublished - 15-Jun-2017
Externally publishedYes

Cite this