Identification by genotyping of a commercial antigen preparation as the source of a laboratory contamination with Coxiella burnetii and as an unexpected rich source of control DNA

Jeroen J. H. C. Tilburg, Alphons M. Horrevorts, Marcel F. Peeters, Corne H. W. Klaassen*, John W. A. Rossen

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    6 Citations (Scopus)

    Abstract

    By performing genotyping, a laboratory contamination involving Q fever was traced back to the antigen preparation used in a commercially available complement fixation test. It was established that such antigen preparations contain relatively high loads of DNA/RNA, making them potential sources of contamination but also convenient preparations for control material.

    Original languageEnglish
    Pages (from-to)383-384
    Number of pages2
    JournalJournal of Clinical Microbiology
    Volume49
    Issue number1
    DOIs
    Publication statusPublished - Jan-2011

    Keywords

    • Complement Fixation Tests
    • Coxiella burnetii
    • DNA Contamination
    • Humans
    • Reagent Kits, Diagnostic
    • Q-FEVER

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