IL-1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergy

M E Ketelaar; Cd Westerlaken van Ginkel; M C Nawijn; A.E.J. Dubois; G H Koppelman

doi:10.1111/cea.13802

IL-1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergy

M E Ketelaar^*, Cd Westerlaken van Ginkel, M C Nawijn, A.E.J. Dubois, G H Koppelman

^*Corresponding author for this work

Groningen Research Institute for Asthma and COPD (GRIAC)

Research output: Contribution to journal › Letter › Academic › peer-review

5 Citations (Scopus)

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Abstract

Food allergy is a common disorder in the Western world, with increasing prevalence and substantial healthcare costs(1). Food allergy is often accompanied by the presence of specific IgE against harmless proteins in food, but not all sensitized children show clinical reactions upon exposure. Therefore, double-blind placebo-controlled food challenges (DBPCFC) remain the gold standard to diagnose food allergy, yet this test is demanding. Biomarkers that can predict clinical response to food are urgently needed.

Original language	English
Pages (from-to)	614-619
Number of pages	6
Journal	Clinical and Experimental Allergy
Volume	51
Issue number	4
Early online date	5-Dec-2020
DOIs	https://doi.org/10.1111/cea.13802
Publication status	Published - Apr-2021

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IL‐1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergyFinal publisher's version, 447 KBLicence: CC BY-NC-ND

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abstract = "Food allergy is a common disorder in the Western world, with increasing prevalence and substantial healthcare costs(1). Food allergy is often accompanied by the presence of specific IgE against harmless proteins in food, but not all sensitized children show clinical reactions upon exposure. Therefore, double-blind placebo-controlled food challenges (DBPCFC) remain the gold standard to diagnose food allergy, yet this test is demanding. Biomarkers that can predict clinical response to food are urgently needed.",

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AU - Ketelaar, M E

AU - van Ginkel, Cd Westerlaken

AU - Nawijn, M C

AU - Dubois, A.E.J.

AU - Koppelman, G H

PY - 2021/4

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N2 - Food allergy is a common disorder in the Western world, with increasing prevalence and substantial healthcare costs(1). Food allergy is often accompanied by the presence of specific IgE against harmless proteins in food, but not all sensitized children show clinical reactions upon exposure. Therefore, double-blind placebo-controlled food challenges (DBPCFC) remain the gold standard to diagnose food allergy, yet this test is demanding. Biomarkers that can predict clinical response to food are urgently needed.

AB - Food allergy is a common disorder in the Western world, with increasing prevalence and substantial healthcare costs(1). Food allergy is often accompanied by the presence of specific IgE against harmless proteins in food, but not all sensitized children show clinical reactions upon exposure. Therefore, double-blind placebo-controlled food challenges (DBPCFC) remain the gold standard to diagnose food allergy, yet this test is demanding. Biomarkers that can predict clinical response to food are urgently needed.

U2 - 10.1111/cea.13802

DO - 10.1111/cea.13802

M3 - Letter

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EP - 619

JO - Clinical and Experimental Allergy

JF - Clinical and Experimental Allergy

IS - 4

ER -

IL-1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergy

Abstract

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