Improved Diagnostic Validity of the ADOS Revised Algorithms: A Replication Study in an Independent Sample

Iris Oosterling*, Sascha Roos, Annelies de Bildt, Nanda Rommelse, Maretha de Jonge, Janne Visser, Martijn Lappenschaar, Sophie Swinkels, Rutger Jan van der Gaag, Jan Buitelaar

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    Recently, Gotham et al. (2007) proposed revised algorithms for the Autism Diagnostic Observation Schedule (ADOS) with improved diagnostic validity. The aim of the current study was to replicate predictive validity, factor structure, and correlations with age and verbal and nonverbal IQ of the ADOS revised algorithms for Modules 1 and 2 in a large independent Dutch sample (N = 532). Results showed that the improvement of diagnostic validity was most apparent for autism, except in very young or low functioning children. Results for other autism spectrum disorders were less consistent. Overall, these findings support the use of the more homogeneous revised algorithms, with the use of similar items across developmental cells making it easier to compare ADOS scores within and between individuals.

    Original languageEnglish
    Pages (from-to)689-703
    Number of pages15
    JournalJournal of Autism and Developmental Disorders
    Volume40
    Issue number6
    DOIs
    Publication statusPublished - Jun-2010

    Keywords

    • Autism
    • ADOS
    • Algorithm
    • Sensitivity
    • Specificity
    • Diagnosis
    • AUTISM SPECTRUM DISORDERS
    • PERVASIVE DEVELOPMENTAL DISORDERS
    • OBSERVATION-SCHEDULE
    • CHILDREN
    • ADOLESCENTS
    • INTERVIEW
    • CRITERIA

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