Improved health status of severe COPD patients after being included in an integrated primary care service: A prospective cohort study

Corina de Jong, Job F. M. van Boven, Michiel R. de Boer*, Janwillem W. H. Kocks, Marjolein Y. Berger, Thys van der Molen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Background Chronic obstructive pulmonary disease (COPD) is a prevalent lung disease. It is assumed that severe patients will receive better treatment in specialised care centres but the prevalence of severe COPD in primary care is high. Integrated primary care services combine input from several sources and advice from pulmonologists to provide general practitioners with support needed to improve diagnosis and treatment of patients with COPD. Objectives To evaluate patient-reported outcomes and costs of managing patients classified as GOLD D in an integrated primary care service over 12 months. Methods Patients were included in this 1-year prospective cohort study if they met the 2014 GOLD D criteria, were aged >= 40 years and gave written informed consent for this study. Recruitment took place through the patients' general practitioners. The primary outcome was health status, assessed with the Clinical COPD Questionnaire (CCQ) and COPD Assessment Test (CAT). Secondary outcomes included self-reported exacerbations, quality-adjusted life years and health(care)-related costs. Results Forty-nine patients were included. At baseline, the mean CAT score was 15.9 and the median CCQ score was 1.7. After 12 months, scores had improved by 2.3 (95% confidence interval, 0.8-3.7) and 0.4 (95% confidence interval, 0.2-0.7), respectively. Percentage of patients with >= 2 exacerbations in the past 12 months also decreased from baseline (77.6%) to 12 months (16.7%). Changes in mean quarterly costs were small. Conclusion An integrated service for COPD based in primary care may improve the health status of patients with a large burden of disease while not increasing health care costs.

Original languageEnglish
Pages (from-to)66-74
Number of pages9
JournalThe European journal of general practice
Issue number1
Publication statusPublished - 31-Dec-2022


  • Asthma
  • COPD
  • Health care organisation and management
  • integrated care
  • longitudinal designs
  • non-experimental
  • treatment
  • intervention research
  • health care economics

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