Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

Dirk van Lier, Matthijs Kox*, Karine Santos, Hans van der Hoeven, Janesh Pillay, Peter Pickkers

*Corresponding author for this work

    Research output: Contribution to journalLetterAcademicpeer-review

    47 Citations (Scopus)
    28 Downloads (Pure)


    Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation

    Original languageEnglish
    Article number00848
    Number of pages4
    JournalERJ Open Research
    Issue number1
    Publication statusPublished - 1-Jan-2021

    Cite this