Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

Dirk van Lier; Matthijs Kox; Karine Santos; Hans van der Hoeven; Janesh Pillay; Peter Pickkers

doi:10.1183/23120541.00848-2020

Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

Dirk van Lier, Matthijs Kox^*, Karine Santos, Hans van der Hoeven, Janesh Pillay, Peter Pickkers

^*Corresponding author for this work

Research output: Contribution to journal › Letter › Academic › peer-review

47 Citations (Scopus)

28 Downloads (Pure)

Abstract

Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation https://bit.ly/2MU1z4z.

Original language	English
Article number	00848
Number of pages	4
Journal	ERJ Open Research
Volume	7
Issue number	1
DOIs	https://doi.org/10.1183/23120541.00848-2020
Publication status	Published - 1-Jan-2021

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10.1183/23120541.00848-2020Licence: CC BY-NC

Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patientsFinal publisher's version, 424 KBLicence: CC BY-NC

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@article{9222edcb08f64db9ac9aba90d099490f,

title = "Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients",

abstract = "Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation https://bit.ly/2MU1z4z.",

author = "{van Lier}, Dirk and Matthijs Kox and Karine Santos and {van der Hoeven}, Hans and Janesh Pillay and Peter Pickkers",

note = "Copyright {\textcopyright}The authors 2021.",

year = "2021",

month = jan,

day = "1",

doi = "10.1183/23120541.00848-2020",

language = "English",

volume = "7",

journal = "ERJ Open Research",

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publisher = "European Respiratory Society",

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TY - JOUR

T1 - Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

AU - van Lier, Dirk

AU - Kox, Matthijs

AU - Santos, Karine

AU - van der Hoeven, Hans

AU - Pillay, Janesh

AU - Pickkers, Peter

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation https://bit.ly/2MU1z4z.

AB - Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation https://bit.ly/2MU1z4z.

U2 - 10.1183/23120541.00848-2020

DO - 10.1183/23120541.00848-2020

M3 - Letter

C2 - 33738305

SN - 2312-0541

VL - 7

JO - ERJ Open Research

JF - ERJ Open Research

IS - 1

M1 - 00848

ER -