@inbook{17dfcaa22401404fbe2afd48c258fb0c,
title = "Induction of Bile Canaliculi-Forming Hepatocytes from Human Pluripotent Stem Cells",
abstract = "Cell polarity and formation of bile canaliculi can be achieved in hepatocytes which are generated from patient-derived induced pluripotent stem cells. This allows for the study of endogenous mutant proteins, patient-specific pathogenesis, and drug responses for diseases where hepatocyte polarity and bile canaliculi play a key role. Here, we describe a step-by-step protocol for the generation of bile canaliculi-forming hepatocytes from induced pluripotent stem cells and their evaluation.",
keywords = "Bile canaliculus, Hepatocyte, Hepatocyte polarity, Induced pluripotent stem cell, Inherited liver disease",
author = "Lavinija Matakovic and Overeem, {Arend W.} and Karin Klappe and {van IJzendoorn}, {Sven C.D.}",
note = "Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2022",
month = sep,
day = "21",
doi = "10.1007/978-1-0716-2557-6_4",
language = "English",
isbn = "978-1-0716-2556-9",
series = "Methods in Molecular Biology",
publisher = "Humana Press",
pages = "71--82",
editor = "Naoki Tanimizu",
booktitle = "Hepatocytes",
}