Infections and inflammatory diseases as risk factors for venous thrombosis A systematic review

Y. I. G. Vladimir Tichelaar*, Hanneke J. C. Kluin-Nelemans, Karina Meijer

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

68 Citations (Scopus)

Abstract

Inflammation and venous thrombosis are intertwined. Only in the recent 15 years clinical epidemiological studies have focussed on inflammatory or infectious diseases as risk factors for venous thrombosis. Although a few reviews and many case reports or studies on these topic has been written, a review reporting relative or absolute risks for venous thrombosis has not been published yet. We performed a systematic review using Medline, Pubmed and Embase and found 31 eligible articles. Inflammatory bowel disease, ANCA-associated vasculitis, infections in general and more specifically, human immunodeficiency virus, pneumonia and urinary tract infections are associated with an increased risk of venous thrombosis.

Original languageEnglish
Pages (from-to)827-837
Number of pages11
JournalThrombosis and Haemostasis
Volume107
Issue number5
DOIs
Publication statusPublished - May-2012

Keywords

  • Venous thrombosis
  • inflammatory diseases
  • infections
  • risk factors
  • C-REACTIVE PROTEIN
  • DEEP-VEIN THROMBOSIS
  • HUMAN-IMMUNODEFICIENCY-VIRUS
  • TUMOR-NECROSIS-FACTOR
  • BOWEL-DISEASE
  • PULMONARY-EMBOLISM
  • ENDOTHELIAL-CELLS
  • IN-VIVO
  • CYTOMEGALOVIRUS-INFECTION
  • RHEUMATOID-ARTHRITIS

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