Influences of Complex Topography and Biochemistry on Mesenchymal Stem Cell Differentiation

Liangliang Yang

doi:10.33612/diss.146104615

Influences of Complex Topography and Biochemistry on Mesenchymal Stem Cell Differentiation

Liangliang Yang

Research output: Thesis › Thesis fully internal (DIV)

984 Downloads (Pure)

Abstract

Overall, the work presented in this thesis demonstrates the importance of topography, which mimic the structure of ECM, and also biochemical cues (e.g., cell-derived extracellular matrix), for directing the cells toward various lineage, e.g., osteogenesis, neurogenesis. These evidences could provide more insight and useful tools to investigate the interaction between topography and stem cells, which could facilitate the development of tissue engineering and regenerative medicine.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Groningen
Supervisors/Advisors	van Rijn, Patrick, Supervisor van Kooten, Theo, Co-supervisor
Award date	7-Dec-2020
Place of Publication	[Groningen]
Publisher	University of Groningen
DOIs	https://doi.org/10.33612/diss.146104615
Publication status	Published - 2020

Access to Document

10.33612/diss.146104615

Title and contentsFinal publisher's version, 309 KB
Chapter 1Final publisher's version, 495 KB
Chapter 2Final publisher's version, 3.1 MB
Chapter 3Final publisher's version, 1.76 MB
Chapter 4Final publisher's version, 1.8 MB
Chapter 5Final publisher's version, 2.79 MB
Chapter 6Final publisher's version, 2.58 MB
Chapter 7Final publisher's version, 1.86 MB
Chapter 8Final publisher's version, 347 KB
AppendicesFinal publisher's version, 276 KB
Complete thesisFinal publisher's version, 13.2 MB
PropositionsFinal publisher's version, 100 KB

Handle.net

Persistent link

Cite this

@phdthesis{ec01a58264564b7db2c550916dd58034,

title = "Influences of Complex Topography and Biochemistry on Mesenchymal Stem Cell Differentiation",

abstract = "Overall, the work presented in this thesis demonstrates the importance of topography, which mimic the structure of ECM, and also biochemical cues (e.g., cell-derived extracellular matrix), for directing the cells toward various lineage, e.g., osteogenesis, neurogenesis. These evidences could provide more insight and useful tools to investigate the interaction between topography and stem cells, which could facilitate the development of tissue engineering and regenerative medicine.",

author = "Liangliang Yang",

year = "2020",

doi = "10.33612/diss.146104615",

language = "English",

publisher = "University of Groningen",

school = "University of Groningen",

}

TY - BOOK

T1 - Influences of Complex Topography and Biochemistry on Mesenchymal Stem Cell Differentiation

AU - Yang, Liangliang

PY - 2020

Y1 - 2020

N2 - Overall, the work presented in this thesis demonstrates the importance of topography, which mimic the structure of ECM, and also biochemical cues (e.g., cell-derived extracellular matrix), for directing the cells toward various lineage, e.g., osteogenesis, neurogenesis. These evidences could provide more insight and useful tools to investigate the interaction between topography and stem cells, which could facilitate the development of tissue engineering and regenerative medicine.

AB - Overall, the work presented in this thesis demonstrates the importance of topography, which mimic the structure of ECM, and also biochemical cues (e.g., cell-derived extracellular matrix), for directing the cells toward various lineage, e.g., osteogenesis, neurogenesis. These evidences could provide more insight and useful tools to investigate the interaction between topography and stem cells, which could facilitate the development of tissue engineering and regenerative medicine.

U2 - 10.33612/diss.146104615

DO - 10.33612/diss.146104615

M3 - Thesis fully internal (DIV)

PB - University of Groningen

CY - [Groningen]

ER -

Influences of Complex Topography and Biochemistry on Mesenchymal Stem Cell Differentiation

Abstract

Access to Document

Handle.net

Fingerprint

Cite this