Influences of Complex Topography and Biochemistry on Mesenchymal Stem Cell Differentiation

Liangliang Yang

    Research output: ThesisThesis fully internal (DIV)

    713 Downloads (Pure)


    Overall, the work presented in this thesis demonstrates the importance of topography, which mimic the structure of ECM, and also biochemical cues (e.g., cell-derived extracellular matrix), for directing the cells toward various lineage, e.g., osteogenesis, neurogenesis. These evidences could provide more insight and useful tools to investigate the interaction between topography and stem cells, which could facilitate the development of tissue engineering and regenerative medicine.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    • van Rijn, Patrick, Supervisor
    • van Kooten, Theo, Co-supervisor
    Award date7-Dec-2020
    Place of Publication[Groningen]
    Publication statusPublished - 2020

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