Initiated CVD of poly(2-hydroxyethyl methacrylate) hydrogels: Synthesis, characterization and in-vitro biocompatibility

Ranjita K. Bose, Kenneth K.S. Lau

Research output: Contribution to journalArticleAcademicpeer-review

33 Citations (Scopus)

Abstract

Initiated (i)CVD, an all-dry, one-step surface polymerization technique, was used to synthesize thin film hydrogels of poly (2-hydroxyethyl methacrylate) (PHEMA). Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopies showed stoichiometric PHEMA films obtained by iCVD. Differential scanning calorimetry (DSC) revealed a high glass transition temperature, indicative of high molecular mass polymer. In-vitro cell studies using adult human dermal fibroblasts (HDF) demonstrated the nontoxic nature and good cell adhesion properties of iCVD PHEMA films.

Original languageEnglish
Pages (from-to)150-155
Number of pages6
JournalChemical Vapor Deposition
Volume15
Issue number4-6
DOIs
Publication statusPublished - Jun-2009
Externally publishedYes

Keywords

  • Cell adhesion
  • Cytotoxicity
  • Hydrogel
  • Initiated CVD
  • PHE

Cite this