Abstract
An insulinoma is a neuroendocrine tumor of the pancreas, arising from the β-cell, resulting in endogenous hyperinsulinemia. This causes hypoglycemia with neurogycopenic symptoms. Diagnosis of insulinoma starts with demonstrating elevated insulin during a spontaneous hypoglycemia or a hypoglycemia can be provoked by a 72-h fasting test. Most insulinomas are benign and localized to the pancreas and can be surgically resected. Rare metastastic insulinomas are treated with diazoxide or somatostatin analogues.
Original language | English |
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Title of host publication | Encyclopedia of Endocrine Diseases |
Editors | Ilpo Huhtaniemi, Luciano Martini |
Publisher | Elsevier |
Pages | 58-62 |
Edition | 2 |
ISBN (Print) | 978-0-12-812200-6 |
DOIs | |
Publication status | Published - 2019 |
Externally published | Yes |