Insulinoma

Wouter T. Zandee, Wouter W. de Herder

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

An insulinoma is a neuroendocrine tumor of the pancreas, arising from the β-cell, resulting in endogenous hyperinsulinemia. This causes hypoglycemia with neurogycopenic symptoms. Diagnosis of insulinoma starts with demonstrating elevated insulin during a spontaneous hypoglycemia or a hypoglycemia can be provoked by a 72-h fasting test. Most insulinomas are benign and localized to the pancreas and can be surgically resected. Rare metastastic insulinomas are treated with diazoxide or somatostatin analogues.
Original languageEnglish
Title of host publicationEncyclopedia of Endocrine Diseases
EditorsIlpo Huhtaniemi, Luciano Martini
PublisherElsevier
Pages58-62
Edition2
ISBN (Print)978-0-12-812200-6
DOIs
Publication statusPublished - 2019
Externally publishedYes

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