Interprofessional Consensus Regarding Design Requirements for Liquid-Based Perinatal Life Support (PLS) Technology

PLS Consortium, Dutch Consortium, M. Beatrijs van der Hout van der Jagt*, E. J. T. Verweij, Peter Andriessen, Willem P. de Boode, Arend F. Bos, Frank L. M. Delbressine, Alex J. Eggink, Jan Jaap H. M. Erwich, Loe M. G. Feijs, Floris Groenendaal, Boris W. W. Kramer, A. Titia Lely, Rachel F. A. M. Loop, Franziska Neukamp, Wes Onland, Martijn A. Oudijk, Arjan B. te Pas, Irwin K. M. ReissMark Schoberer, Ralph R. Scholten, Marc E. A. Spaanderman, Myrthe van der Ven, Marijn J. Vermeulen, Frans N. van de Vosse, S. Guid Oei

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Liquid-based perinatal life support (PLS) technology will probably be applied in a first-in-human study within the next decade. Research and development of PLS technology should not only address technical issues, but also consider socio-ethical and legal aspects, its application area, and the corresponding design implications. This paper represents the consensus opinion of a group of healthcare professionals, designers, ethicists, researchers and patient representatives, who have expertise in tertiary obstetric and neonatal care, bio-ethics, experimental perinatal animal models for physiologic research, biomedical modeling, monitoring, and design. The aim of this paper is to provide a framework for research and development of PLS technology. These requirements are considering the possible respective user perspectives, with the aim to co-create a PLS system that facilitates physiological growth and development for extremely preterm born infants.

Original languageEnglish
Article number793531
Number of pages8
JournalFrontiers in Pediatrics
Publication statusPublished - 19-Jan-2022


  • perinatal life support
  • artificial placenta
  • AAPT
  • user perspectives
  • design implications
  • value-sensitive design


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