Abstract
In summary
CIF is a complex condition that deserves intense multidisciplinary care. HPN is the mainstay of treatment with good survival rates despite frequent serious complications, psychosocial and physical distress and substantial costs. ITx can be a cost-effective alternative treatment for a selected number of CIF patients that fail on HPN therapy. International online registration and monitoring of CIF patients aids multidisciplinary care and facilitates adequate and timely referral for screening and ITx. Such a registry is difficult to establish but absolutely crucial to improve best practice and results of ITx. Valid criteria to select good donor grafts, better insight into transplant-related intestinal graft damage and the development of a tailor-made intestinal preservation technique will improve outcomes after ITx.
To date, HPN and ITx are both challenging medical therapies applied to allow patients with CIF -a
life-threatening condition- to survive with a reasonable quality of life. The decision-making for the best medical regimen when intestinal failure occurs is definitely a team-effort. The treatment of CIF has to be tailored for each individual patient allowing all medical knowledge to be present and providing dedicated care with great patience.
CIF is a complex condition that deserves intense multidisciplinary care. HPN is the mainstay of treatment with good survival rates despite frequent serious complications, psychosocial and physical distress and substantial costs. ITx can be a cost-effective alternative treatment for a selected number of CIF patients that fail on HPN therapy. International online registration and monitoring of CIF patients aids multidisciplinary care and facilitates adequate and timely referral for screening and ITx. Such a registry is difficult to establish but absolutely crucial to improve best practice and results of ITx. Valid criteria to select good donor grafts, better insight into transplant-related intestinal graft damage and the development of a tailor-made intestinal preservation technique will improve outcomes after ITx.
To date, HPN and ITx are both challenging medical therapies applied to allow patients with CIF -a
life-threatening condition- to survive with a reasonable quality of life. The decision-making for the best medical regimen when intestinal failure occurs is definitely a team-effort. The treatment of CIF has to be tailored for each individual patient allowing all medical knowledge to be present and providing dedicated care with great patience.
| Original language | English |
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| Qualification | Doctor of Philosophy |
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| Supervisors/Advisors |
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| Award date | 18-Jun-2014 |
| Place of Publication | [S.l.] |
| Publisher | |
| Print ISBNs | 978-90-367-7037-8 |
| Electronic ISBNs | 978-90-367-7036-1 |
| Publication status | Published - 2014 |