Involvement of the chromosomal region 11q13 in renal oncocytoma: Case report and literature review

C Neuhaus, T Dijkhuizen, E vandenBerg, S Storkel, M Stockle, B Mensch, C Huber, HJ Decker

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    Abstract

    Renal oncocytomas comprise a cytogenetically heterogeneous group of tumors consisting potentially of cytogenetic distinguishable subgroups. Review of the literature revealed loss of chromosome 1 and Y as a possible anomaly for at least one subset of oncocytomas. The frequent finding of rearrangements involving chromosome 11 band q13 characterizes another subset of oncocytomas. We report the cytogenetic and pathological features of a renal oncocytoma diagnosed in a 72-year-old woman and found a t(9;11)(p23;q13) as a consistent abnormality. This supports the idea that translocations involving 11q13 define a further subset of oncocytoma. (C) Elsevier Science Inc., 1997.

    Original languageEnglish
    Pages (from-to)95-98
    Number of pages4
    JournalCancer Genetics and Cytogenetics
    Volume94
    Issue number2
    Publication statusPublished - Apr-1997

    Keywords

    • CYTOGENETIC ABNORMALITIES
    • TUMORS
    • LOCALIZATION
    • GENE

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