Abstract
A patient with 'spent' polycythaemia vera showed extensive extramedullary haematopoiesis (EMH) in non-haematopoietic tissue clinically resulting in an ischaemic colitis and respiratory symptoms due to lung infiltrates. On laboratory investigation, the EMH also included immature erythroblasts due to acute erythroid leukaemia. It is hypothesised that the abnormal homing of erythroid progenitors might be related to the abnormal expression of antigens, such as CD36. (C) 1998 Elsevier Science B.V.
Original language | English |
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Pages (from-to) | 142-146 |
Number of pages | 5 |
Journal | Netherlands Journal of Medicine |
Volume | 52 |
Issue number | 4 |
Publication status | Published - Apr-1998 |
Keywords
- polycythemia vera (PV)
- extramedullary hematopoiesis (EMH)
- acute leukemia (AL)
- CD36
- AGNOGENIC MYELOID METAPLASIA
- POLYCYTHEMIA-VERA
- ACUTE-LEUKEMIA
- PLASMODIUM-FALCIPARUM
- ENDOTHELIAL-CELLS
- SPLENECTOMY
- MYELOFIBROSIS
- PROGENITORS
- BLOOD