KRS: A cut away from release in exosomes

Catherine Rabouille*

*Corresponding author for this work

    Research output: Contribution to journalEditorialAcademicpeer-review

    2 Citations (Scopus)
    202 Downloads (Pure)

    Abstract

    Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyltRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.

    Original languageEnglish
    Pages (from-to)1891-1893
    Number of pages3
    JournalThe Journal of Cell Biology
    Volume216
    Issue number7
    DOIs
    Publication statusPublished - 3-Jul-2017

    Keywords

    • SECRETION
    • BIOGENESIS
    • ALIX

    Cite this