Language Processing in Neurodegenerative Diseases: Semantic, Phonological, and Grammatical Impairments in Alzheimer’s Disease, Parkinson’s Disease, and Frontotemporal Lobar Degeneration – A Linguistic Overview

Fedor Jalvingh, Roelien Bastiaanse, Roel Jonkers

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    Abstract

    Disorders of language and/or communicative abilities in neurodegenerative diseases are a common phenomenon. Over the past few
    decades, there has been a growing interest in language performance connected to these diseases. To date, studies in the fi eld of language impairments in Alzheimer’s disease (AD), Parkinson’s disease (PD), and frontotemporal lobar degeneration (FTLD) have focused mainly on particular aspects of language processing in the isolated disease or on comparing certain language tasks in two neurodegenerative diseases. To enable a better understanding and comparison of the underlying linguistic defi cits in all three disorders, this paper focuses on phonological, semantic, and grammatical processing in each of the disorders. A review of the literature on language processing defi cits reveals that phonological, semantic, and grammatical processing is impaired in the early stages of AD, PD, and FTLD, and that the underlying defi cits are sometimes linguistic in nature. Language disorders, however, may also refl ect cognitive defi cits, such as short-term verbal memory impairments,
    attention defi cits, and reduced switching capacities, all of which have an impact on language processing
    Original languageEnglish
    Pages (from-to)49-62
    Number of pages13
    JournalZeitschrift für Neuropsychologie
    Volume30
    Issue number1
    DOIs
    Publication statusPublished - Mar-2019

    Keywords

    • phonological
    • semantic
    • grammatical processing
    • neurodegenerative diseases
    • PRIMARY PROGRESSIVE APHASIA
    • ALZHEIMERS-DISEASE
    • SENTENCE COMPREHENSION
    • PARKINSONS-DISEASE
    • SEMANTIC DEMENTIA
    • LOGOPENIC VARIANT
    • PHONOLOGICAL ERRORS
    • BASAL GANGLIA
    • FRONTOTEMPORAL DEGENERATION
    • INFLECTIONAL MORPHOLOGY

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