Left ventricular ejection fraction and mortality in patients with ST-elevation myocardial infarction and bundle branch block

M. Yldau van der Ende; Minke H. T. Hartman; Tom Hendriks; Hindrik W. van der Werf; Erik Lipsic; Pim van der Harst

doi:10.1097/MCA.0000000000000456

Left ventricular ejection fraction and mortality in patients with ST-elevation myocardial infarction and bundle branch block

M. Yldau van der Ende, Minke H. T. Hartman, Tom Hendriks, Hindrik W. van der Werf, Erik Lipsic, Pim van der Harst^*

^*Corresponding author for this work

Cardiovascular Centre (CVC)

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Background The aim of our study is to assess the effect of bundle branch block (BBB) on mortality and left ventricular ejection fraction (LVEF) in ST-elevation myocardial infarction (STEMI) patients treated in the current era of percutaneous reperfusion therapy.

Patients and methods In this retrospective cohort study, a total of 1123 STEMI patients treated in the University Medical Center Groningen from January 2011 until May 2013 were included. The follow-up duration was 2-4 years. Transthoracic echocardiography was performed within 2 weeks after STEMI.

Results In total, 23 (2.0%) patients presented with left BBB and 49 (4.4%) patients presented with right BBB. Two-year mortality after STEMI was 25.0% (n=18) in patients with BBB and 9.2% (n=97, P

Conclusion The presence of a BBB was an independent predictor of a reduced LVEF. However, we found no effect of BBB on 2-year mortality in the current era of percutaneous reperfusion therapy. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

Original language	English
Pages (from-to)	232-238
Number of pages	7
Journal	Coronary artery disease
Volume	28
Issue number	3
DOIs	https://doi.org/10.1097/MCA.0000000000000456
Publication status	Published - 1-May-2017

Keywords

bundle branch block
percutaneous reperfusion therapy
ST-elevation myocardial infarction
PERCUTANEOUS CORONARY INTERVENTION
LONG-TERM SURVIVAL
CLINICAL CHARACTERISTICS
THROMBOLYTIC THERAPY
DILATED CARDIOMYOPATHY
PRIMARY ANGIOPLASTY
ELECTROCARDIOGRAM
RECOMMENDATIONS
ASSOCIATION
PROGNOSIS

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10.1097/MCA.0000000000000456

Left ventricular ejection fraction and mortality in patients with ST-elevation myocardial infarction and bundle branch blockFinal publisher's version, 225 KBLicence: Taverne

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@article{f17acc68690c4600ad515255161b64f7,

title = "Left ventricular ejection fraction and mortality in patients with ST-elevation myocardial infarction and bundle branch block",

abstract = "Background The aim of our study is to assess the effect of bundle branch block (BBB) on mortality and left ventricular ejection fraction (LVEF) in ST-elevation myocardial infarction (STEMI) patients treated in the current era of percutaneous reperfusion therapy.Patients and methods In this retrospective cohort study, a total of 1123 STEMI patients treated in the University Medical Center Groningen from January 2011 until May 2013 were included. The follow-up duration was 2-4 years. Transthoracic echocardiography was performed within 2 weeks after STEMI.Results In total, 23 (2.0%) patients presented with left BBB and 49 (4.4%) patients presented with right BBB. Two-year mortality after STEMI was 25.0% (n=18) in patients with BBB and 9.2% (n=97, PConclusion The presence of a BBB was an independent predictor of a reduced LVEF. However, we found no effect of BBB on 2-year mortality in the current era of percutaneous reperfusion therapy. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.",

keywords = "bundle branch block, percutaneous reperfusion therapy, ST-elevation myocardial infarction, PERCUTANEOUS CORONARY INTERVENTION, LONG-TERM SURVIVAL, CLINICAL CHARACTERISTICS, THROMBOLYTIC THERAPY, DILATED CARDIOMYOPATHY, PRIMARY ANGIOPLASTY, ELECTROCARDIOGRAM, RECOMMENDATIONS, ASSOCIATION, PROGNOSIS",

author = "{van der Ende}, {M. Yldau} and Hartman, {Minke H. T.} and Tom Hendriks and {van der Werf}, {Hindrik W.} and Erik Lipsic and {van der Harst}, Pim",

year = "2017",

month = may,

day = "1",

doi = "10.1097/MCA.0000000000000456",

language = "English",

volume = "28",

pages = "232--238",

journal = "Coronary artery disease",

issn = "0954-6928",

publisher = "LIPPINCOTT WILLIAMS & WILKINS",

number = "3",

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TY - JOUR

T1 - Left ventricular ejection fraction and mortality in patients with ST-elevation myocardial infarction and bundle branch block

AU - van der Ende, M. Yldau

AU - Hartman, Minke H. T.

AU - Hendriks, Tom

AU - van der Werf, Hindrik W.

AU - Lipsic, Erik

AU - van der Harst, Pim

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Background The aim of our study is to assess the effect of bundle branch block (BBB) on mortality and left ventricular ejection fraction (LVEF) in ST-elevation myocardial infarction (STEMI) patients treated in the current era of percutaneous reperfusion therapy.Patients and methods In this retrospective cohort study, a total of 1123 STEMI patients treated in the University Medical Center Groningen from January 2011 until May 2013 were included. The follow-up duration was 2-4 years. Transthoracic echocardiography was performed within 2 weeks after STEMI.Results In total, 23 (2.0%) patients presented with left BBB and 49 (4.4%) patients presented with right BBB. Two-year mortality after STEMI was 25.0% (n=18) in patients with BBB and 9.2% (n=97, PConclusion The presence of a BBB was an independent predictor of a reduced LVEF. However, we found no effect of BBB on 2-year mortality in the current era of percutaneous reperfusion therapy. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

AB - Background The aim of our study is to assess the effect of bundle branch block (BBB) on mortality and left ventricular ejection fraction (LVEF) in ST-elevation myocardial infarction (STEMI) patients treated in the current era of percutaneous reperfusion therapy.Patients and methods In this retrospective cohort study, a total of 1123 STEMI patients treated in the University Medical Center Groningen from January 2011 until May 2013 were included. The follow-up duration was 2-4 years. Transthoracic echocardiography was performed within 2 weeks after STEMI.Results In total, 23 (2.0%) patients presented with left BBB and 49 (4.4%) patients presented with right BBB. Two-year mortality after STEMI was 25.0% (n=18) in patients with BBB and 9.2% (n=97, PConclusion The presence of a BBB was an independent predictor of a reduced LVEF. However, we found no effect of BBB on 2-year mortality in the current era of percutaneous reperfusion therapy. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

KW - bundle branch block

KW - percutaneous reperfusion therapy

KW - ST-elevation myocardial infarction

KW - PERCUTANEOUS CORONARY INTERVENTION

KW - LONG-TERM SURVIVAL

KW - CLINICAL CHARACTERISTICS

KW - THROMBOLYTIC THERAPY

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KW - PRIMARY ANGIOPLASTY

KW - ELECTROCARDIOGRAM

KW - RECOMMENDATIONS

KW - ASSOCIATION

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DO - 10.1097/MCA.0000000000000456

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