Left ventricular ejection fraction and mortality in patients with ST-elevation myocardial infarction and bundle branch block

M. Yldau van der Ende, Minke H. T. Hartman, Tom Hendriks, Hindrik W. van der Werf, Erik Lipsic, Pim van der Harst*

*Corresponding author for this work

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Abstract

Background The aim of our study is to assess the effect of bundle branch block (BBB) on mortality and left ventricular ejection fraction (LVEF) in ST-elevation myocardial infarction (STEMI) patients treated in the current era of percutaneous reperfusion therapy.

Patients and methods In this retrospective cohort study, a total of 1123 STEMI patients treated in the University Medical Center Groningen from January 2011 until May 2013 were included. The follow-up duration was 2-4 years. Transthoracic echocardiography was performed within 2 weeks after STEMI.

Results In total, 23 (2.0%) patients presented with left BBB and 49 (4.4%) patients presented with right BBB. Two-year mortality after STEMI was 25.0% (n=18) in patients with BBB and 9.2% (n=97, P

Conclusion The presence of a BBB was an independent predictor of a reduced LVEF. However, we found no effect of BBB on 2-year mortality in the current era of percutaneous reperfusion therapy. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

Original languageEnglish
Pages (from-to)232-238
Number of pages7
JournalCoronary artery disease
Volume28
Issue number3
DOIs
Publication statusPublished - 1-May-2017

Keywords

  • bundle branch block
  • percutaneous reperfusion therapy
  • ST-elevation myocardial infarction
  • PERCUTANEOUS CORONARY INTERVENTION
  • LONG-TERM SURVIVAL
  • CLINICAL CHARACTERISTICS
  • THROMBOLYTIC THERAPY
  • DILATED CARDIOMYOPATHY
  • PRIMARY ANGIOPLASTY
  • ELECTROCARDIOGRAM
  • RECOMMENDATIONS
  • ASSOCIATION
  • PROGNOSIS

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