Lewis Acids in Autocatalytic and Dearomative Reactions

    Research output: ThesisThesis fully internal (DIV)

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    Abstract

    This thesis encloses the application of Lewis acids (LAs) in autocatalytic and dearomative reactions. In both cases, LA is invoked to change the reactivity of starting materials. Thus, in the case of autocatalysis, studied reactions proceed with increasing Lewis acidity of the media. The enhanced acidity allows reaction rate enhancement. In chapter 6, dearomatization of naphthols is enabled in virtue of coordination of LA to the aromatic compound. This coordination proceeds with the formation of ketone intermediate, which reacts with nucleophiles resulting in dearomatized products.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    Supervisors/Advisors
    • Harutyunyan, Syuzanna, Supervisor
    • Browne, Wesley, Co-supervisor
    Award date24-Sep-2021
    Place of Publication[Groningen]
    Publisher
    DOIs
    Publication statusPublished - 2021

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