Abstract
Obesity decreases the chance to conceive naturally and after infertility treatment. Obesity is also associated with anovulation and it increases risks of complications during pregnancy. We investigated, in the thesis Lifestyle intervention in obese infertile women, if weight loss prior to infertility treatment could help women with obesity to increase their natural conception chances and reduce complication rates during pregnancy. Data of 577 women in The Netherlands, who participated in the LIFEstyle study were investigated.
The results of the LIFEstyle study show that, in obese infertile women, participating in a six-month lifestyle intervention before commencing infertility treatment induces weight loss, improves quality of life and improves risk factors for cardiovascular disease. The intervention did not improve the chance of a healthy baby within two years. The intervention did, however, improve the chance of having a natural conception, especially in women with an ovulatory disorder, such as polycystic ovary syndrome. Costs of infertility treatment were lower in women who participated in the lifestyle intervention.
This thesis shows strong arguments to advocate weight loss prior to infertility treatment.
The results of the LIFEstyle study show that, in obese infertile women, participating in a six-month lifestyle intervention before commencing infertility treatment induces weight loss, improves quality of life and improves risk factors for cardiovascular disease. The intervention did not improve the chance of a healthy baby within two years. The intervention did, however, improve the chance of having a natural conception, especially in women with an ovulatory disorder, such as polycystic ovary syndrome. Costs of infertility treatment were lower in women who participated in the lifestyle intervention.
This thesis shows strong arguments to advocate weight loss prior to infertility treatment.
Original language | English |
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Qualification | Doctor of Philosophy |
Awarding Institution |
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Supervisors/Advisors |
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Award date | 22-Nov-2017 |
Place of Publication | [Groningen] |
Publisher | |
Print ISBNs | 978-94-034-0208-6 |
Electronic ISBNs | 978-94-034-0207-9 |
Publication status | Published - 2017 |