Lifestyle intervention in obese infertile women

Anne Maria van Oers

    Research output: ThesisThesis fully internal (DIV)

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    Obesity decreases the chance to conceive naturally and after infertility treatment. Obesity is also associated with anovulation and it increases risks of complications during pregnancy. We investigated, in the thesis Lifestyle intervention in obese infertile women, if weight loss prior to infertility treatment could help women with obesity to increase their natural conception chances and reduce complication rates during pregnancy. Data of 577 women in The Netherlands, who participated in the LIFEstyle study were investigated.
    The results of the LIFEstyle study show that, in obese infertile women, participating in a six-month lifestyle intervention before commencing infertility treatment induces weight loss, improves quality of life and improves risk factors for cardiovascular disease. The intervention did not improve the chance of a healthy baby within two years. The intervention did, however, improve the chance of having a natural conception, especially in women with an ovulatory disorder, such as polycystic ovary syndrome. Costs of infertility treatment were lower in women who participated in the lifestyle intervention.
    This thesis shows strong arguments to advocate weight loss prior to infertility treatment.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    • Hoek, Annemieke, Supervisor
    • Mol, B.W.J., Supervisor, External person
    • Groen, Henk, Co-supervisor
    • Buskens, Erik, Assessment committee
    • de Groot, C. J. M., Assessment committee, External person
    • Goddijn, M., Assessment committee, External person
    Award date22-Nov-2017
    Place of Publication[Groningen]
    Print ISBNs978-94-034-0208-6
    Electronic ISBNs978-94-034-0207-9
    Publication statusPublished - 2017

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