@article{68a879784ca7475c9976b202d7292eef,
title = "Ligand-free palladium catalysed Heck reaction of methyl 2-acetamido acrylate and aryl bromides as key step in the synthesis of enantiopure substituted phenylalanines",
abstract = "A range of substituted aryl bromides were coupled with methyl 2-acetamido acrylate using ligand-free palladium catalysis. Subsequently asymmetric hydrogenation with Rh/MonoPhos yielded substituted phenylalanines in high enantioselectivities (e.e. 92-99%).",
author = "Willans, {Charlotte E.} and Mulders, {Jan M.C.A.} and Vries, {Johannes G. de} and Vries, {Andr{\'e} H.M. de}",
note = "Relation: http://www.rug.nl/scheikunde/ date_submitted:2006 Rights: University of Groningen. Stratingh Institute",
year = "2003",
doi = "10.1016/j.jorganchem.2003.09.012",
language = "English",
volume = "687",
journal = "Journal of Organometallic Chemistry",
publisher = "Elsevier Science",
number = "2",
}