Light-induced molecular rotation triggers on-demand release from liposomes

Laís Ribovski, Qihui Zhou, Jiawen Chen, Ben L Feringa, Patrick van Rijn*, Inge S Zuhorn

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
15 Downloads (Pure)

Abstract

Controllable molecular release from delivery vehicles is essential to successfully reduce drug toxicity and improve therapeutic efficacy. Light-powered hydrophobic molecular motors were therefore incorporated in liposomes to use molecular rotation to facilitate on-demand release. The extent of the release was precisely controlled by irradiation times, providing a simple yet sophisticated responsive molecular nanocarrier. This journal is

Original languageEnglish
Pages (from-to)8774-8777
Number of pages4
JournalChemical communications (Cambridge, England)
Volume56
Issue number62
Early online date3-Jul-2020
DOIs
Publication statusPublished - 11-Aug-2020

Keywords

  • NANOMEDICINE
  • DELIVERY
  • MOTORS

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