Lipid Nanotechnology

Samaneh Mashaghi, Tayebeh Jadidi, Gijsje Koenderink, Alireza Mashaghi*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

185 Citations (Scopus)
332 Downloads (Pure)

Abstract

Nanotechnology is a multidisciplinary field that covers a vast and diverse array of devices and machines derived from engineering, physics, materials science, chemistry and biology. These devices have found applications in biomedical sciences, such as targeted drug delivery, bio-imaging, sensing and diagnosis of pathologies at early stages. In these applications, nano-devices typically interface with the plasma membrane of cells. On the other hand, naturally occurring nanostructures in biology have been a source of inspiration for new nanotechnological designs and hybrid nanostructures made of biological and non-biological, organic and inorganic building blocks. Lipids, with their amphiphilicity, diversity of head and tail chemistry, and antifouling properties that block nonspecific binding to lipid-coated surfaces, provide a powerful toolbox for nanotechnology. This review discusses the progress in the emerging field of lipid nanotechnology.

Original languageEnglish
Pages (from-to)4242-4282
Number of pages41
JournalInternational Journal of Molecular Sciences
Volume14
Issue number2
DOIs
Publication statusPublished - 21-Feb-2013

Keywords

  • soft nanotechnology
  • supramolecular chemistry
  • hybrid materials
  • synthetic biology
  • self-assembly
  • nanoparticle
  • nanomedicine
  • nanofluidics
  • nanoelectronics
  • lab-on-a-chip
  • MOLECULAR-DYNAMICS SIMULATION
  • DISSIPATIVE PARTICLE DYNAMICS
  • SUPPORTED PHOSPHOLIPID-BILAYERS
  • ATOMIC-FORCE MICROSCOPY
  • WALLED CARBON NANOTUBES
  • IONIC CHARGE IMBALANCE
  • LIQUID-ORDERED-PHASE
  • COARSE-GRAINED MODEL
  • VESICLE FUSION
  • DRUG-DELIVERY

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