Abstract
The development of a complex multicellular organ such as the nervous system requires precise regulation of cell migration, proliferation and survival. This regulation in turn requires the integration of long-range signals, such as growth factors, with short-range cues that define the precise location and cellular neighbours for any given cell. This short review examines one integrative mechanism, integrin-growth factor receptor interactions, and explores the role of lipid rafts in the molecular mechanisms that underlie the receptor interactions.
| Original language | English |
|---|---|
| Pages (from-to) | 426-430 |
| Number of pages | 5 |
| Journal | Biochemical Society Transactions |
| Volume | 32 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Jun-2004 |
| Externally published | Yes |
Keywords
- Apoptosis
- Laminin
- Oligodendrocyte
- Platelet-derived growth factor (PDGF)