TY - JOUR
T1 - Locally Advanced Colon Cancer
T2 - Evaluation of Current Clinical Practice and Treatment Outcomes at the Population Level
AU - Klaver, Charlotte E. L.
AU - Gietelink, Lieke
AU - Bemelman, Willem A.
AU - Wouters, Michel W. J. M.
AU - Wiggers, Theo
AU - Tollenaar, Rob A. E. M.
AU - Tanis, Pieter J.
AU - Dutch Surgical Colorectal Audit Gr
PY - 2017/2
Y1 - 2017/2
N2 - Background: The goal of this study was to evaluate current clinical practice and treatment outcomes regarding locally advanced colon cancer (LACC) at the population level. Methods: Data were used from the Dutch Surgical Colorectal Audit from 2009 to 2014. A total of 34,527 patients underwent resection for non-LACC and 6,918 for LACC, which was defined as cT4 and/or pT4 stage. LACC was divided into those with multivisceral resection (LACC-MV; n=3,385) and without (LACC-noMV; n=1,595). Guideline adherence, treatment strategy, and short-term outcomes were evaluated. Results: Guideline adherence was >90% regarding preoperative imaging and 80% regarding preoperative multidisciplinary team (MDT) discussion. In the elective setting, neoadjuvant chemoradiotherapy (chemoRT) was applied in 6.2% of the cT4 cases, and neoadjuvant chemotherapy in 4.0%. RO resection rates were 99%, 91%, and 87% in patients with non-LACC, LACCnoMV, and LACC-MV, respectively (P
AB - Background: The goal of this study was to evaluate current clinical practice and treatment outcomes regarding locally advanced colon cancer (LACC) at the population level. Methods: Data were used from the Dutch Surgical Colorectal Audit from 2009 to 2014. A total of 34,527 patients underwent resection for non-LACC and 6,918 for LACC, which was defined as cT4 and/or pT4 stage. LACC was divided into those with multivisceral resection (LACC-MV; n=3,385) and without (LACC-noMV; n=1,595). Guideline adherence, treatment strategy, and short-term outcomes were evaluated. Results: Guideline adherence was >90% regarding preoperative imaging and 80% regarding preoperative multidisciplinary team (MDT) discussion. In the elective setting, neoadjuvant chemoradiotherapy (chemoRT) was applied in 6.2% of the cT4 cases, and neoadjuvant chemotherapy in 4.0%. RO resection rates were 99%, 91%, and 87% in patients with non-LACC, LACCnoMV, and LACC-MV, respectively (P
KW - ADVANCED COLORECTAL-CANCER
KW - MULTIVISCERAL RESECTION
KW - OPEN SURGERY
KW - NEOADJUVANT CHEMORADIOTHERAPY
KW - LAPAROSCOPIC RESECTION
KW - MARGIN INVOLVEMENT
KW - T4
KW - PANCREATICODUODENECTOMY
KW - CARCINOMA
U2 - 10.6004/jnccn.2017.0019
DO - 10.6004/jnccn.2017.0019
M3 - Article
SN - 1540-1405
VL - 15
SP - 181
EP - 190
JO - Journal of the national comprehensive cancer network
JF - Journal of the national comprehensive cancer network
IS - 2
ER -