TY - JOUR
T1 - Low-Temperature and Solventless Ring-Opening Polymerization of Eutectic Mixtures of l-Lactide and Lactones for Biodegradable Polyesters
AU - Castillo-Santillan, Martín
AU - Maniar, Dina
AU - Gutiérrez, María C.
AU - Quiñonez-Angulo, Priscila
AU - Torres-Lubian, José Román
AU - Loos, Katja
AU - Mota-Morales, Josué D.
N1 - Funding Information:
The authors gratefully acknowledge the financial support received from PAPIIT-UNAM through grant IA206022, the Zernike Institute for Advanced Materials, and the University of Groningen (UG). They also thank Jur van Dijken (UG-Zernike) for the technical assistance provided in acquiring DSC and TGA thermograms, Albert J. J. Woortman (UG-Zernike) for obtaining GPC chromatograms, Pieter van der Meulen for obtaining DOSY spectra, and Guillermo Vazquez (CFATA-UNAM). Priscila Quiñonez-Angulo acknowledges the support provided for this research through a post-doctoral fellowship from the National Council of Science and Technology (CONACYT) of Mexico.
Publisher Copyright:
© 2023 American Chemical Society.
PY - 2023/7/14
Y1 - 2023/7/14
N2 - Biodegradability is one of the key features for reducing the negative environmental impact of plastic waste disposal; therefore, designing biocompatible polymeric biomaterials with programmable life cycles is urgently needed. Herein, deep eutectic solvent monomers (DESm) composed of l-lactide and various lactones of different molecular weights were formulated to obtain polyesters at low temperatures with the aid of organocatalysts and under solventless conditions. The introduced DESm expand the range of eutectic mixtures capable of undergoing ring-opening polymerization (ROP) to include mixtures of l-lactide with δ-valerolactone and δ-hexalactone. Extending the toolbox for DESm preparation will allow for the design of polyesters with tailored molecular weight and crystallinity, which are conducive to programmable degradability. ROP of DESm carried out at low temperatures and under solventless conditions holds promise for a sustainable framework for preparing biodegradable polymers for biomedical applications.
AB - Biodegradability is one of the key features for reducing the negative environmental impact of plastic waste disposal; therefore, designing biocompatible polymeric biomaterials with programmable life cycles is urgently needed. Herein, deep eutectic solvent monomers (DESm) composed of l-lactide and various lactones of different molecular weights were formulated to obtain polyesters at low temperatures with the aid of organocatalysts and under solventless conditions. The introduced DESm expand the range of eutectic mixtures capable of undergoing ring-opening polymerization (ROP) to include mixtures of l-lactide with δ-valerolactone and δ-hexalactone. Extending the toolbox for DESm preparation will allow for the design of polyesters with tailored molecular weight and crystallinity, which are conducive to programmable degradability. ROP of DESm carried out at low temperatures and under solventless conditions holds promise for a sustainable framework for preparing biodegradable polymers for biomedical applications.
KW - deep eutectic solvent monomers: valerolactone
KW - lactide
KW - polyesters
KW - ring opening polymerization
UR - http://www.scopus.com/inward/record.url?scp=85164489422&partnerID=8YFLogxK
U2 - 10.1021/acsapm.3c00591
DO - 10.1021/acsapm.3c00591
M3 - Article
AN - SCOPUS:85164489422
SN - 2637-6105
VL - 5
SP - 5110
EP - 5121
JO - ACS Applied Polymer Materials
JF - ACS Applied Polymer Materials
IS - 7
ER -