Lymphatic drainage patterns of oral maxillary tumors: Approachable locations of sentinel lymph nodes mainly at the cervical neck level

Koos Boeve*, Kees-Pieter Schepman, Bert van der Vegt, Ed Schuuring, Jan L. Roodenburg, Adrienne H. Brouwers, Max J. Witjes

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Abstract

Background. There is debate if the lymphatic drainage pattern of oral maxillary cancer is to the retropharyngeal lymph nodes or to the cervical lymph nodes. Insight in drainage patterns is important for the indication for neck treatment. The purpose of this study was to identify the lymphatic drainage pattern of oral maxillary cancer via preoperative lymphoscintigraphy.

Methods. Eleven consecutive patients with oral maxillary cancer treated in our center between December 1, 2012, and April 22, 2016 were studied. Sentinel lymph nodes identified by preoperative lymphoscintigraphy after injection of Tc-99m-nanocolloid and by intraoperative detection using a gamma-probe, were surgically removed and histopathologically examined.

Results. In 10 patients, sentinel lymph nodes were detected and harvested at cervical levels I, II, or III in the neck. In 2 patients, a parapharyngeal sentinel lymph node was detected. One of the harvested sentinel lymph nodes (1/19) was tumor positive.

Conclusion. This study suggests the likelihood of 73% of exclusively cervical level I to III sentinel lymph nodes in oral maxillary cancer. (C) 2016 Wiley Periodicals, Inc.

Original languageEnglish
Pages (from-to)486-491
Number of pages6
JournalHead and Neck: Journal of the Sciences and Specialties of the Head and Neck
Volume39
Issue number3
DOIs
Publication statusPublished - Mar-2017

Keywords

  • oral maxillary cancer
  • sentinel lymph node
  • lymphatic drainage pattern
  • sentinel lymph node biopsy
  • lymphoscintigraphy
  • SQUAMOUS-CELL CARCINOMA
  • HARD PALATE
  • DISSECTION
  • CANCER
  • ALVEOLUS
  • BIOPSY
  • METASTASIS
  • RATIONALE
  • TRIAL

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