Manganese-Catalyzed Selective Oxidation of Aliphatic C-H groups and Secondary Alcohols to Ketones with Hydrogen Peroxide

Jia Jia Dong, Duenpen Unjaroen, Francesco Mecozzi, Emma C. Harvey, Pattama Saisaha, Dirk Pijper, Johannes W. de Boer, Paul Alsters, Ben L. Feringa, Wesley R. Browne*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)
737 Downloads (Pure)

Abstract

An efficient and simple method for selective oxidation of secondary alcohols and oxidation of alkanes to ketones is reported. An insitu prepared catalyst is employed based on manganese(II) salts, pyridine-2-carboxylic acid, and butanedione, which provides good-to-excellent conversions and yields with high turnover numbers (up to 10000) with H2O2 as oxidant at ambient temperatures. In substrates bearing multiple alcohol groups, secondary alcohols are converted to ketones selectively and, in general, benzyl CH oxidation proceeds in preference to aliphatic CH oxidation.

Original languageEnglish
Pages (from-to)1774-1778
Number of pages5
JournalChemsuschem
Volume6
Issue number9
DOIs
Publication statusPublished - 14-Sept-2013

Keywords

  • alcohol oxidation
  • alkane oxidation
  • catalysis
  • manganese
  • AEROBIC OXIDATION
  • METAL CATALYSIS
  • ACETIC-ACID
  • COMPLEX
  • MOLYBDENUM
  • ALKANES
  • EFFICIENT
  • METHYLTRIOXORHENIUM
  • HYDROXYLATION
  • SYSTEM

Fingerprint

Dive into the research topics of 'Manganese-Catalyzed Selective Oxidation of Aliphatic C-H groups and Secondary Alcohols to Ketones with Hydrogen Peroxide'. Together they form a unique fingerprint.

Cite this