Abstract
The invention relates to the field of medicine. In particular, it relates to means and methods for reducing or avoiding the acquisition of antibiotic resistance. Provided is an agent capable of reducing the proton motive force (PMF) in bacteria for use in reducing or preventing the acquisition of antibiotic resistance of a commensal bacterium, like Streptococcus pneumoniae, that resides in the nasopharynx of a mammalian subject, wherein the use is not for the purpose of carrying out therapy on the human or animal body.
| Original language | English |
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| Patent number | WO2018070874 |
| Priority date | 12/10/2016 |
| Publication status | Published - 19-Apr-2018 |