Means and methods for the N-dealkylation of amines

Tao Yuan (Inventor), Rainer Paul Hermann Bischoff (Inventor), Hjalmar Petrus Permentier (Inventor)

Research output: Patent


The invention relates to improved means and methods for N- dealkylation of alkylated amines. Provided is a method for the catalytic N- dealkylation of an N-alkylated amine substrate, comprising incubating said amine substrate in a suitable solvent in the presence of a nanoporous gold (NPG) surface and allowing for the formation of an N-dealkylation product. Also provided is a reaction mixture comprising an N-alkylated amine substrate in a suitable solvent and a NPG surface.
Original languageEnglish
Patent numberWO2017179976
Priority date14/04/2016
Publication statusPublished - 19-Oct-2017

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