Measurement of quality of life in head and neck cancer patients utilizing the quality of life radiation therapy questionnaire

Monika Janda, Darlene Johnson, Hedwig Woelfl, Michael Trimmel, Tim Bressmann, Heidi Schröckmayr, Joachim Widder, Andy Trotti

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)

Abstract

Background: Quality of life (QOL) measures give patients the possibility to express subjective changes in wellbeing. We aimed to translate the radiation specific quality of life questionnaire (QOL-RTI) and the companion head and neck module (H&N) questionnaire into German and to test its reliability, validity and sensitivity.

Patients and Methods: After translation and final revisions based on qualitative interviews with ten patients, 97 head and neck cancer patients were screened for eligibility. Patients answered the 38 items questionnaire at baseline and twice in week 4 of radiotherapy for test-retest reliability. Internal consistency was calculated using Chronbach's alpha. Patients also completed the functional assessment of cancer tool plus head and neck (FACT-G plus H&N) for concurrent validity. Item analyses were performed to test the sensitivity.

Results: Chronbach's alpha yielded alpha = 0.85 for the QOL-RTI and alpha = 0.80 for the H&N module, test-retest reliability scores were r = 0.87 and r = 0.83, respectively. The correlation of the QOL-RTI plus H&N and the FACT plus H&N was r = 0.79. Questionnaire sensitivity was supported by significant changes in the mean score of 45.8% of the QOL-RTI items and 78.6% of the H&N items between baseline and week 4 of radiotherapy.

Conclusions: The German version of the QOL-RTI was shown to be a reliable, valid and sensitive tool. to assess the quality of life of patients undergoing radiotherapy. The H&N module is useful for patients undergoing treatment for head and neck cancer.

Original languageEnglish
Pages (from-to)153-158
Number of pages6
JournalStrahlentherapie und onkologie
Volume178
Issue number3
DOIs
Publication statusPublished - Mar-2002
Externally publishedYes

Keywords

  • radiotherapy
  • head and neck cancer
  • quality of life
  • questionnaire
  • psychosocial support
  • SQUAMOUS-CELL CARCINOMA
  • LOCALLY ADVANCED HEAD
  • OF-LIFE
  • EUROPEAN-ORGANIZATION
  • FUNCTIONAL ASSESSMENT
  • CONCOMITANT CHEMORADIOTHERAPY
  • RADIOTHERAPY
  • PERFORMANCE
  • INSTRUMENT
  • MODULE

Fingerprint

Dive into the research topics of 'Measurement of quality of life in head and neck cancer patients utilizing the quality of life radiation therapy questionnaire'. Together they form a unique fingerprint.

Cite this