Mechanochemical endovenous ablation in the treatment of varicose veins

Ramon van Eekeren

    Research output: ThesisThesis fully internal (DIV)

    6531 Downloads (Pure)


    Varicose veins are a common disease. Symptoms of varicose veins can range from mild itching or fatigue to severe ulceration.

    For more than a hundred years, stripping of the varicose vein has been the main treatment. However, in the last decade, minimally invasive techniques have been developed to improve the effectiveness, disease-related quality of life and the cosmetic outcome. Most endovenous (catheter) techniques use heat to obliterate the varicose vein and are therefore performed under tumescent anesthesia. This includes the application of multiple injections with saline and lidocaine around the varicose vein, which has an analgesic effect. It also ensures good buffering of the heat that is released during, for example, laser- or radiofrequency ablation. These injections are time consuming and painful for patients. In addition, heat-related complications such as skin burns, nerve damage and prolonged pain are described.

    Mechanochemical endovenous ablation (MOCA) is a minimally invasive technique without the use of heat. Therefore, tumescent anesthesia has become obsolete and heat-related complications are prevented. MOCA uses the ClariVein system to obliterate varicose veins. With the use of a rotating wire, a sclerosing liquid (sclerosant) is injected in the varicose vein, that attaches to the inside of the vein. The varicose vein shrinks and then disappears.

    In this thesis, we have demonstrated that MOCA is a safe, feasible and effective treatment for varicose veins. In comparison with radiofrequency ablation, MOCA is associated with less pain during and after the treatment. This results in a faster recovery and return to work.
    Translated title of the contributionMechanochemische endoveneuze ablatie bij de behandeling van spataderen
    Original languageEnglish
    QualificationDoctor of Philosophy
    Awarding Institution
    • University of Groningen
    • Zeebregts, Clark, Supervisor
    • Wittens, C.H.A., Supervisor, External person
    • Reijnen, M.M.P.J., Co-supervisor, External person
    • de Vries, Jean-Paul, Co-supervisor
    Award date1-Apr-2015
    Place of Publication[S.l.]
    Print ISBNs978-90-9028872-7
    Publication statusPublished - 2015


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