Microdialysis glucose sensor system compared with needle type glucose sensor in vivo during OGTT and physical exercise

B. U. Moon*, K. J. C. Wientjes, A. J. M. Schoonen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)

Abstract

The 'subcutaneous glucose monitoring system' (SCGM) is based on microdialysis and allows continuous glucose monitoring in abdominal adipose tissue of diabetic patients up to 5 days. In the current in vivo study we compared the SCGM system with a commercially available needle type glucose sensor during an oral glucose tolerance test (OGTT) and during physical exercise. The SCGM had a good in vivo performance that was comparable to the needle type sensor. The inherent safe measuring technology of microdialysis and sensor stability of the SCGM makes it a likely candidate for online glucose measurement in diabetic patients. However, the overall system configuration is too bulky to wear comfortably and the measured values have a time lag of 35 min. The SCGM system will be the base for the future development of a miniaturized integrated microdialysis sensor system using labon-a-chip technology.

Original languageEnglish
Title of host publication2006 IEEE SENSORS, VOLS 1-3
Place of PublicationNEW YORK
PublisherIEEE (The Institute of Electrical and Electronics Engineers)
Pages1000-1003
Number of pages4
ISBN (Print)978-1-4244-0375-2
Publication statusPublished - 2006
Event5th IEEE Sensors Conference -
Duration: 22-Oct-200625-Oct-2006

Publication series

NameIEEE Sensors
PublisherIEEE
ISSN (Print)1930-0395

Other

Other5th IEEE Sensors Conference
Period22/10/200625/10/2006

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