Microfluidic capture and release of bacteria in a conical nanopore array

Peng Guo, Eric W Hall, Romana Schirhagl, Hitomi Mukaibo, Charles R Martin, Richard N Zare

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)

Abstract

We present a simple and inexpensive method for the capture and
release of bacteria contained in an array of conical nanopores on
a membrane inside a microfluidic device. As an example, we
demonstrate that cyanobacteria can be captured, one bacterium per
pore, in a defined orientation with over 500 bacteria per membrane
with viabilities as high as 100%. The device can also specifically
capture cyanobacteria from a mixed suspension of cyanobacteria
and chlamydomonas with a selectivity as high as 90%.
Original languageEnglish
Pages (from-to)558-561
Number of pages4
JournalLab on a Chip - Miniaturisation for Chemistry and Biology
Volume12
Issue number3
DOIs
Publication statusPublished - 2012
Externally publishedYes

Fingerprint

Dive into the research topics of 'Microfluidic capture and release of bacteria in a conical nanopore array'. Together they form a unique fingerprint.

Cite this