Microfluidic manipulation with artificial/bioinspired cilia

Jaap M. J. den Toonder*, Patrick R. Onck

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

142 Citations (Scopus)

Abstract

A recent development, inspired by nature, is the use of 'artificial cilia' to create pumping and/or mixing in microfluidic devices. Cilia are small hairs that can be found in biology and are used for (fluid) actuation and sensing. Microscopic actuators resembling cilia, actuated to move under the influence of various stimuli such as electrostatic field, magnetic field, and even light, have been developed by a number of groups and shown to be capable of generating flow and mixing in microfluidic environments. The research on artificial cilia started about a decade ago and is rapidly expanding. In addition to being relevant for potential application in lab-on-a-chip devices, the work on artificial cilia forms a beautiful example of how a biological system can form the successful basis for both scientific research and technological applications. In this review, we will give an overview of the most important approaches in this exciting field.

Original languageEnglish
Pages (from-to)85-91
Number of pages7
JournalTrends in Biotechnology
Volume31
Issue number2
DOIs
Publication statusPublished - Feb-2013

Keywords

  • artificial cilia
  • microfluidics
  • biomimetics
  • ACTUATED ARTIFICIAL CILIA
  • BIOMIMETIC CILIA
  • ARRAYS

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