Abstract
In a multifactorial experiment, dermal sheep collagen was treated in diluted glutaraldehyde solutions, 70% ethyl alcohol, Cialit 1:5000, and distilled water for 1, 3 and 5 min, respectively, in combination with microwave irradiation at different temperature settings. The shrinkage temperature indicating the degree of cross-linking achieved was then determined. Treatment in 0.65% glutaraldehyde with microwave irradiation setting for 60-degrees-C resulted in the maximum shrinkage temperature within 1 min, whilst at the lower setting of 50-degrees-C the maximum shrinkage temperature for both glutaraldehyde solutions is only reached after 5 min. Neither microwave irradiation by itself, Cialit or ethyl alcohol induce cross-linking of collagen fibres. These findings are relevant for implant studies.
| Original language | English |
|---|---|
| Pages (from-to) | 34-37 |
| Number of pages | 4 |
| Journal | Biomaterials |
| Volume | 13 |
| Issue number | 1 |
| Publication status | Published - 1992 |
Keywords
- GLUTARALDEHYDE FIXATION
- MICROWAVE IRRADIATION
- COLLAGEN
- FIXATION