Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021

Artur J. Sabat, Erik Bathoorn, Monika A. Chlebowicz-Fliss, Viktoria Akkerboom, Inge Kamphuis, Claudy Oliveira Dos Santos, Alexander W. Friedrich*

*Corresponding author for this work

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Abstract

We describe two false-negative results in the detection of meticillin-resistant Staphylococcus aureus (MRSA) of sequence type 398 and spa type t011 using the Cepheid Xpert MRSA NxG assay. The isolates were recovered in late February and early March 2021 from two patients in different hospitals in the northern Netherlands. Variations between the two isolate genomes indicate that this MRSA strain might have been spreading for some time and could have disseminated to other regions of the Netherlands and other European countries.

Original languageEnglish
Article number2100800
Number of pages6
JournalEurosurveillance
Volume26
Issue number37
DOIs
Publication statusPublished - 16-Sep-2021

Keywords

  • Europe
  • Humans
  • Methicillin
  • Methicillin-Resistant Staphylococcus aureus/genetics
  • Netherlands/epidemiology
  • Staphylococcal Infections/diagnosis

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