Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma

Natália Pinto de Almeida; Ágnes Judit Jánosi; Runyu Hong; Ahmad Rajeh; Fábio Nogueira; Leticia Szadai; Beata Szeitz; Indira Pla Parada; Viktória Doma; Nicole Woldmar; Jéssica Guedes; Zsuzsanna Újfaludi; Aron Bartha; Yonghyo Kim; Charlotte Welinder; Bo Baldetorp; Lajos Vince Kemény; Zoltan Pahi; Guihong Wan; Nga Nguyen; Tibor Pankotai; Balázs Győrffy; Krzysztof Pawłowski; Peter Horvatovich; Attila Marcell Szasz; Aniel Sanchez; Magdalena Kuras; Jimmy Rodriguez Murillo; Lazaro Betancourt; Gilberto B Domont; Yevgeniy R Semenov; Kun-Hsing Yu; Ho Jeong Kwon; István Balázs Németh; David Fenyő; Elisabet Wieslander; György Marko-Varga; Jeovanis Gil

doi:10.1002/ctm2.1773

Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma

Natália Pinto de Almeida, Ágnes Judit Jánosi, Runyu Hong, Ahmad Rajeh, Fábio Nogueira, Leticia Szadai, Beata Szeitz, Indira Pla Parada, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Újfaludi, Aron Bartha, Yonghyo Kim, Charlotte Welinder, Bo Baldetorp, Lajos Vince Kemény, Zoltan Pahi, Guihong Wan, Nga NguyenTibor Pankotai, Balázs Győrffy, Krzysztof Pawłowski, Peter Horvatovich, Attila Marcell Szasz, Aniel Sanchez, Magdalena Kuras, Jimmy Rodriguez Murillo, Lazaro Betancourt, Gilberto B Domont, Yevgeniy R Semenov, Kun-Hsing Yu, Ho Jeong Kwon, István Balázs Németh, David Fenyő, Elisabet Wieslander, György Marko-Varga, Jeovanis Gil

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Original language	English
Article number	e1773
Number of pages	9
Journal	Clinical and Translational Medicine
Volume	14
Issue number	7
DOIs	https://doi.org/10.1002/ctm2.1773
Publication status	Published - Jul-2024

Keywords

Humans
Melanoma/genetics
Proto-Oncogene Proteins B-raf/genetics
Mutation
Mitochondria/genetics
Male
Female
Middle Aged
Neoplasm Metastasis/genetics

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Pinto de Almeida, N., Jánosi, Á. J., Hong, R., Rajeh, A., Nogueira, F., Szadai, L., Szeitz, B., Pla Parada, I., Doma, V., Woldmar, N., Guedes, J., Újfaludi, Z., Bartha, A., Kim, Y., Welinder, C., Baldetorp, B., Kemény, L. V., Pahi, Z., Wan, G., ... Gil, J. (2024). Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma. Clinical and Translational Medicine, 14(7), Article e1773. https://doi.org/10.1002/ctm2.1773

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title = "Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma",

keywords = "Humans, Melanoma/genetics, Proto-Oncogene Proteins B-raf/genetics, Mutation, Mitochondria/genetics, Male, Female, Middle Aged, Neoplasm Metastasis/genetics",

author = "{Pinto de Almeida}, Nat{\'a}lia and J{\'a}nosi, {{\'A}gnes Judit} and Runyu Hong and Ahmad Rajeh and F{\'a}bio Nogueira and Leticia Szadai and Beata Szeitz and {Pla Parada}, Indira and Vikt{\'o}ria Doma and Nicole Woldmar and J{\'e}ssica Guedes and Zsuzsanna {\'U}jfaludi and Aron Bartha and Yonghyo Kim and Charlotte Welinder and Bo Baldetorp and Kem{\'e}ny, {Lajos Vince} and Zoltan Pahi and Guihong Wan and Nga Nguyen and Tibor Pankotai and Bal{\'a}zs Gy{\H o}rffy and Krzysztof Paw{\l}owski and Peter Horvatovich and Szasz, {Attila Marcell} and Aniel Sanchez and Magdalena Kuras and {Rodriguez Murillo}, Jimmy and Lazaro Betancourt and Domont, {Gilberto B} and Semenov, {Yevgeniy R} and Kun-Hsing Yu and Kwon, {Ho Jeong} and N{\'e}meth, {Istv{\'a}n Bal{\'a}zs} and David Feny{\H o} and Elisabet Wieslander and Gy{\"o}rgy Marko-Varga and Jeovanis Gil",

year = "2024",

month = jul,

doi = "10.1002/ctm2.1773",

language = "English",

volume = "14",

journal = "Clinical and Translational Medicine",

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Pinto de Almeida, N, Jánosi, ÁJ, Hong, R, Rajeh, A, Nogueira, F, Szadai, L, Szeitz, B, Pla Parada, I, Doma, V, Woldmar, N, Guedes, J, Újfaludi, Z, Bartha, A, Kim, Y, Welinder, C, Baldetorp, B, Kemény, LV, Pahi, Z, Wan, G, Nguyen, N, Pankotai, T, Győrffy, B, Pawłowski, K, Horvatovich, P, Szasz, AM, Sanchez, A, Kuras, M, Rodriguez Murillo, J, Betancourt, L, Domont, GB, Semenov, YR, Yu, K-H, Kwon, HJ, Németh, IB, Fenyő, D, Wieslander, E, Marko-Varga, G & Gil, J 2024, 'Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma', Clinical and Translational Medicine, vol. 14, no. 7, e1773. https://doi.org/10.1002/ctm2.1773

TY - JOUR

T1 - Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma

AU - Pinto de Almeida, Natália

AU - Jánosi, Ágnes Judit

AU - Hong, Runyu

AU - Rajeh, Ahmad

AU - Nogueira, Fábio

AU - Szadai, Leticia

AU - Szeitz, Beata

AU - Pla Parada, Indira

AU - Doma, Viktória

AU - Woldmar, Nicole

AU - Guedes, Jéssica

AU - Újfaludi, Zsuzsanna

AU - Bartha, Aron

AU - Kim, Yonghyo

AU - Welinder, Charlotte

AU - Baldetorp, Bo

AU - Kemény, Lajos Vince

AU - Pahi, Zoltan

AU - Wan, Guihong

AU - Nguyen, Nga

AU - Pankotai, Tibor

AU - Győrffy, Balázs

AU - Pawłowski, Krzysztof

AU - Horvatovich, Peter

AU - Szasz, Attila Marcell

AU - Sanchez, Aniel

AU - Kuras, Magdalena

AU - Rodriguez Murillo, Jimmy

AU - Betancourt, Lazaro

AU - Domont, Gilberto B

AU - Semenov, Yevgeniy R

AU - Yu, Kun-Hsing

AU - Kwon, Ho Jeong

AU - Németh, István Balázs

AU - Fenyő, David

AU - Wieslander, Elisabet

AU - Marko-Varga, György

AU - Gil, Jeovanis

PY - 2024/7

Y1 - 2024/7

KW - Humans

KW - Melanoma/genetics

KW - Proto-Oncogene Proteins B-raf/genetics

KW - Mutation

KW - Mitochondria/genetics

KW - Male

KW - Female

KW - Middle Aged

KW - Neoplasm Metastasis/genetics

U2 - 10.1002/ctm2.1773

DO - 10.1002/ctm2.1773

M3 - Letter

C2 - 39032005

SN - 2001-1326

VL - 14

JO - Clinical and Translational Medicine

JF - Clinical and Translational Medicine

IS - 7

M1 - e1773

ER -