MitraClip (R) therapy in patients with end-stage systolic heart failure

  • Olaf Franzen*
  • , Jan van der Heyden
  • , Stephan Baldus
  • , Michael Schlueter
  • , Wolfgang Schillinger
  • , Christian Butter
  • , Rainer Hoffmann
  • , Roberto Corti
  • , Giovanni Pedrazzini
  • , Martin J. Swaans
  • , Michael Neuss
  • , Volker Rudolph
  • , Daniel Suerder
  • , Juerg Gruenenfelder
  • , Christine Eulenburg
  • , Hermann Reichenspurner
  • , Thomas Meinertz
  • , Angelo Auricchio
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

285 Citations (Scopus)

Abstract

Aims To assess the feasibility, short-term durability and clinical outcomes of MitraClip (R) therapy for mitral regurgitation (MR) in patients with end-stage heart failure and a severely reduced left ventricular (LV) ejection fraction.

Methods and results We analysed retrospectively collected data from seven European centres. Included in the study were 50 heart failure patients [ mean age 70 +/- 11 years, 38 men (76%)] with a LV ejection fraction

Conclusion MitraClip (R) therapy reduces functional MR in patients with end-stage heart failure and marked LV dysfunction and entails clinical benefit at 6 months.

Original languageEnglish
Pages (from-to)569-576
Number of pages8
JournalEuropean Journal of Heart Failure
Volume13
Issue number5
DOIs
Publication statusPublished - May-2011
Externally publishedYes

Keywords

  • Heart failure
  • Heart valves
  • Mitral regurgitation
  • Catheter-based therapy
  • ISCHEMIC MITRAL REGURGITATION
  • CARDIAC RESYNCHRONIZATION THERAPY
  • VALVE ANNULOPLASTY
  • CLINICAL-TRIAL
  • SEVERITY
  • IMPACT
  • DYSFUNCTION
  • REPAIR
  • ECHOCARDIOGRAPHY
  • RISK

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