Modeling the effects of influenza vaccination of health care workers in hospital departments

C. van den Dool*, M. J. M. Bonten, E. Hak, J. Wallinga

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    60 Citations (Scopus)

    Abstract

    Nowadays health care worker (HCW) vaccination is widely recommended. Although the benefits of this strategy have been demonstrated in long-term care settings, no studies have been performed in regular hospital departments. We adapt a previously developed model of influenza transmission in a long-term care nursing home department to study the effects of HCW vaccination in hospital wards. We study both the effectiveness and efficiency in reducing the hazard rates of influenza virus infection for patients. Most scenarios under study show a similar or higher impact of hospital HCW vaccination than has been predicted for the long-term care nursing home department. Therefore, it seems justified to extend the recommendations for HCW vaccination, based on results in the long-term care setting, to short-term care settings as well. (C) 2009 Elsevier Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)6261-6267
    Number of pages7
    JournalVaccine
    Volume27
    Issue number44
    DOIs
    Publication statusPublished - 19-Oct-2009

    Keywords

    • Health care worker vaccination
    • Hospital
    • Mathematical model
    • LONG-TERM-CARE
    • RANDOMIZED CONTROLLED-TRIAL
    • MATHEMATICAL-MODEL
    • ELDERLY-PEOPLE
    • TRANSMISSION
    • INFECTION
    • RECOMMENDATIONS
    • TUBERCULOSIS
    • UNCERTAINTY
    • SENSITIVITY

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